3 Results for "

MG-Lin2

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "MG-Lin2" in MCE Product Catalog:

Cat. No.: HY-177732
Research Areas:  

Cancer

MG-Lin2 is a Lin28 molecular glue degrader. It induces the formation of a ternary complex between Lin28 and the E3 ubiquitin ligase RNF126, mediates the degradation of Lin28 via the ubiquitin-proteasome pathway, and restores the abundance and function of mature let-7 miRNA. MG-Lin2 can be used in studies of ovarian cancer and choriocarcinoma .
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Cat. No.: HY-177534
CAS No.: 1252773-92-4
Target:  

MAGL

Research Areas:  

Metabolic Disease

MGL-IN-2 (Compound 1) is a MGL inhibitor with IC50 values of 0.006 μM and 0.0121 μM for mutant MGL and wild-type MGL, respectively. MGL-IN-2 can be used in the research of metabolic diseases .
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Cat. No.: HY-59320
CAS No.: 3973-08-8
4-Thiazolecarboxylic acid (Compound 1e) is an intermediate. 4-Thiazolecarboxylic acid can be used in the synthesis of MGL-IN-2 (HY-177534). MGL-IN-2 inhibits wild-type MGL enzyme activity with an IC50 of 0.0121 μM. 4-Thiazolecarboxylic acid can be used in the research of metabolic diseases .
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