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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
124 Results for "
MIP
" in MedChemExpress (MCE) Product Catalog:
Products (124)
124 Results for "MIP" in MCE Product Catalog:
32
Category:
Neurological Disease Umbelliferae Extract Ketones, Aldehydes, Acids Plants Disease Research Fields Endocrinology Echinacea angustifolia DC. Cancer
Target:
14
14 Cited Publications
Synonyms: Dexamethasone 21-phosphate disodium
Research Areas:
Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate disodium is produced by introducing a phosphate ester group at the 21-position of the Dexamethasone molecule, forming a salt with sodium ions, thereby significantly improving water solubility. Dexamethasone phosphate disodium inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate disodium inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate disodium is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate disodium can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease) .
14
Research Areas:
Dexamethasone phosphate (Dexamethasone 21-phosphate) is a prodrug form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone phosphate is prepared by introducing a phosphate ester group to the hydroxyl group at position 21 of the Dexamethasone molecule. Dexamethasone phosphate inhibits LPS (HY-D1056)-induced degradation of IRAK-1 and IRAK-4, and blocks LPS-induced activation of TRAF6, p-TAK1 and p-JNK. Dexamethasone phosphate inhibits the secretion of RANTES, TGF-β1 and NO, promotes the production of MIP-1α and IL-10, and blocks microglial migration. Dexamethasone phosphate is almost completely converted to Dexamethasone in rat blood, and supports transdermal delivery via iontophoresis. Dexamethasone phosphate can be used in research related to steroid-dependent ulcerative colitis, chemotherapy-induced vomiting, allergic asthma and acute colitis (inflammatory bowel disease) .
4
4 Cited Publications
Cat. No.: HY-P7257
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL4; Act-2; Prev. SCYA4; MIP1B; Prev. LAG1; HC21; MIP-1-Beta; Monocyte Adherence-Induced Protein 5 Alpha; AT744.1; Chemokine C-C Motif Ligand 4; Small Inducible Cytokine A4 (Homologous To Mouse MIP-1b); Small-Inducible Cytokine A4; Macrophage Inflammator
Species:
Human
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P7255
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL3; Tonsillar Lymphocyte LD78 Alpha Protein; Prev. SCYA3; C-C Motif Chemokine 3; MIP-1-Alpha; PAT 464.1; G0S19-1; SIS-Beta; LD78ALPHA; MIP1A; LD78; Macrophage Inflammatory Protein 1 Alpha; SCI; Chemokine (C-C Motif) Ligand 3; Small Inducible Cytokine A3
Species:
Mouse
Source:
HEK293
3
3 Cited Publications
Cat. No.: HY-19974
CAS No.: 333994-00-6
Research Areas:
TAK-220 is a selective and orally bioavailable CCR5 antagonist, with IC50s of 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1α to CCR5, respectively, but shows no effect on the binding to CCR1, CCR2b, CCR3, CCR4, or CCR7; TAK-220 also selectively inhibits HIV-1, with EC50s of 1.2 nM (HIV-1 KK), 0.72 nM (HIV-1 CTV), 1.7 nM (HIV-1 HKW), 1.7 nM (HIV-1 HNK), 0.93 nM (HIV-1 HTN), and 0.55 nM (HIV-1 HHA), and EC90s of 12 nM (HIV-1 KK), 5 nM (HIV-1 CTV), 12 nM (HIV-1 HKW), 28 nM (HIV-1 HNK), 15 nM (HIV-1 HTN), and 4 nM (HIV-1 HHA) in PBMCs.
3
3 Cited Publications
Cat. No.: HY-P7153
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL3; C-X-C Motif Chemokine 3; Prev. GRO3; GRO3 Oncogene; SCYB3; GRO-Gamma; CINC-2b; MIP2-Beta; MIP-2b; Melanoma Growth Stimulatory Activity Gamma; GROg; MGSA Gamma; Macrophage Inflammatory Protein 2-Beta; MIP2B; Chemokine (C-X-C Motif) Ligand 3; GROG; G
Species:
Mouse
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P7190
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL2; Growth-Regulated Protein Beta; Prev. GRO2; GRO2 Oncogene; SCYB2; MIP2-Alpha; CINC-2a; Gro-Beta; MGSA-B; MIP2A; MIP-2a; Melanoma Growth Stimulatory Activity Beta; GROb; MGSA Beta; Macrophage Inflammatory Protein 2-Alpha; MIP2; Chemokine (C-X-C Motif
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P7260
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL20; Chemokine (C-C Motif) Ligand 20; Prev. SCYA20; C-C Motif Chemokine 20; LARC; CC Chemokine LARC; MIP-3a; MIP-3-Alpha; ST38; Exodus-1; CKb4; MIP3A; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20; Beta Chemokine Exodus-1; Liver And Activati
Species:
Human
Source:
CHO
2
2 Cited Publications
Cat. No.: HY-P7263
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL20; Chemokine (C-C Motif) Ligand 20; Prev. SCYA20; C-C Motif Chemokine 20; LARC; CC Chemokine LARC; MIP-3a; MIP-3-Alpha; ST38; Exodus-1; CKb4; MIP3A; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20; Beta Chemokine Exodus-1; Liver And Activati
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P7258
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL2; Growth-Regulated Protein Beta; Prev. GRO2; GRO2 Oncogene; SCYB2; MIP2-Alpha; CINC-2a; Gro-Beta; MGSA-B; MIP2A; MIP-2a; Melanoma Growth Stimulatory Activity Beta; GROb; MGSA Beta; Macrophage Inflammatory Protein 2-Alpha; MIP2; Chemokine (C-X-C Motif
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P700171AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL2; Growth-Regulated Protein Beta; Prev. GRO2; GRO2 Oncogene; SCYB2; MIP2-Alpha; CINC-2a; Gro-Beta; MGSA-B; MIP2A; MIP-2a; Melanoma Growth Stimulatory Activity Beta; GROb; MGSA Beta; Macrophage Inflammatory Protein 2-Alpha; MIP2; Chemokine (C-X-C Motif
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P7262
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL20; Chemokine (C-C Motif) Ligand 20; Prev. SCYA20; C-C Motif Chemokine 20; LARC; CC Chemokine LARC; MIP-3a; MIP-3-Alpha; ST38; Exodus-1; CKb4; MIP3A; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20; Beta Chemokine Exodus-1; Liver And Activati
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P702526
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL19; Small-Inducible Cytokine A19; Prev. SCYA19; CC Chemokine Ligand 19; ELC; C-C Motif Chemokine 19; CK Beta-11; EBI1-Ligand Chemokine; Exodus-3; MIP-3-Beta; MIP-3b; MIP3B; CKb11; Macrophage Inflammatory Protein 3 Beta; Small Inducible Cytokine Subfami
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P71889
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL4; Act-2; Prev. SCYA4; MIP1B; Prev. LAG1; HC21; MIP-1-Beta; Monocyte Adherence-Induced Protein 5 Alpha; AT744.1; Chemokine C-C Motif Ligand 4; Small Inducible Cytokine A4 (Homologous To Mouse MIP-1b); Small-Inducible Cytokine A4; Macrophage Inflammator
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P7266
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL15; Chemokine (C-C Motif) Ligand 15; Prev. SCYA15; C-C Motif Chemokine 15; HCC-2; Leukotactin 1; NCC-3; NCC3; MIP-5; New CC Chemokine 3; Macrophage Inflammatory Protein 5; CC Chemokine 3; Chemokine CC-2; Leukotactin-1; MIP-1 Delta; MRP-2B; HMRP-2B; Mrp
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P7768
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL3; Tonsillar Lymphocyte LD78 Alpha Protein; Prev. SCYA3; C-C Motif Chemokine 3; MIP-1-Alpha; PAT 464.1; G0S19-1; SIS-Beta; LD78ALPHA; MIP1A; LD78; Macrophage Inflammatory Protein 1 Alpha; SCI; Chemokine (C-C Motif) Ligand 3; Small Inducible Cytokine A3
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P7772
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Scya9; Scya10; Mrp2; Ccl9; Small-inducible cytokine A9; MRP-2; Macrophage inflammatory protein-related protein 2; MIP-1-gamma; Macrophage inflammatory protein 1-gamma; CCF18; C-C motif chemokine 9
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P72683
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL14; Kec; Prev. SCYB14; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 14 (BRAK); NJAC; Chemokine (C-X-C Motif) Ligand 14; Small-Inducible Cytokine B14; Breast And Kidney; C-X-C Motif Chemokine 14; MIP-2G; Chemokine BRAK; MIP2G; Bolekine; CXC
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
