1 Result for "

MK-2060

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MK-2060" in MCE Product Catalog:

Cat. No.: HY-P991581
CAS No.: 2812480-88-7
Target:  

Factor XI

MK-2060 is a monoclonal antibody factor XI inhibitor. MK-2060 binds to the A3 domain of coagulation factor XI (FXI), prevents FXIIa-mediated FXI activation, and blocks the binding/activation of FIX with FXIa, locking the zymogen in an inactive/non-activatable conformation, thereby prolonging aPTT. MK-2060 can be used in research on end-stage renal disease, ESRD requiring hemodialysis, and arteriovenous graft thrombosis .
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