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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
MS432
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "MS432" in MCE Product Catalog:
MS432 is a potent and selective MEK1/MEK2 PRORAC degrader. MS432 specifically degrades MEK1 and MEK2 by recruiting the VHL E3 ligase, thereby potently inhibiting the phosphorylation activation of the downstream ERK pathway. MS432 can be used in research related to colorectal cancer and melanoma .
Cat. No.: HY-W013253
CAS No.: 10436-25-6
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Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432 (HY-130602) .
Cat. No.: HY-115873
CAS No.: 2769735-56-8
Folate-MS432, a PROTAC, is capable of degrading MEKs in a folate receptor-dependent manner in cancer cells.
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Br-C10-methyl ester is a PROTAC linker, which refers to the alkyl/ether composition. Br-C10-methyl ester is used in the synthesis of a series of PROTACs (MS432). PROTACs contain two different ligands connected by a linker; one is the VHL ligand portion and the other is for the target protein .
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(S,R,S)-AHPC-Me-C10-Br is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-Me-C10-Br incorporates a VHL E3 ligase linker and MS432 based on the MEK1/2 inhibitor PD0325901 .
Cat. No.: HY-130847
CAS No.: 2376139-52-3
Research Areas:
(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
