129 Results for "

Main protease

" in MedChemExpress (MCE) Product Catalog:
Products (129)

129 Results for "Main protease" in MCE Product Catalog:

47
Simeprevir
Simeprevir
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47 Publications Verification
Cat. No.: HY-10241
CAS No.: 923604-59-5
Purity:  98.79%
Synonyms: TMC435; TMC435350
Target:  

HCV HCV Protease SARS-CoV DNA/RNA Synthesis

Research Areas:  

Infection

Simeprevir (TMC435; TMC435350) is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a Ki of 0.36 nM. Simeprevir inhibits HCV replication with an EC50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (M pro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses .
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11
Silymarin
Silymarin
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11 Cited Publications
Cat. No.: HY-N7073
CAS No.: 65666-07-1
Category:  

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