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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
125 Results for "
Major compounds
" in MedChemExpress (MCE) Product Catalog:
Products (125)
125 Results for "Major compounds" in MCE Product Catalog:
39
39 Publications Verification
Synonyms: 3-O-Caffeoylquinic acid; Heriguard; NSC-407296
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Tecovirimat (ST-246) is an orally bioavailable and selective compound against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus .
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3 Cited Publications
Synonyms: ST-246 monohydrate
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Tecovirimat (ST-246) monohydrate is the monohydrate form of Tecovirimat (HY-14805). Tecovirimat monohydrate is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat monohydrate is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat monohydrate targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat monohydrate exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat monohydrate could be used in the study for orthopoxvirus-induced diseases .
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1 Cited Publications
Synonyms: Frambione; 4-(4-Hydroxyphenyl)-2-butanone
Category:
Cardiovascular Disease Plant Monophenols Rosaceae Extract Phenols Disease Research Fields Rubus idaeus Linn. Extract
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Plant Zingiberaceae Extract Ketones, Aldehydes, Acids Curcuma longa Extract Disease Research Fields Inflammation/Immunology
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Synonyms: 3-Phenylpropionic acid; 3-Phenylpropanoic acid; 3-Phenyl-n-propionic acid
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Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Prostate Cancer Markers Endogenous metabolite Disease Research Fields Cancer
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Cat. No.: HY-W016388
CAS No.: 1689-64-1
Synonyms: 9-Hydroxyfluorene
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9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 µM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo .
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Cat. No.: HY-W015788
CAS No.: 93-56-1
Synonyms: Styrene Glycol
Cat. No.: HY-124481
CAS No.: 289030-99-5
Synonyms: PTA
Category:
Leguminosae/Fabaceae Extract Plant Caesalpinia sappan L. Extract Phenols Polyphenols Disease Research Fields Inflammation/Immunology
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Synonyms: Isorhamnetin-3,7-diglucoside; Isorhamnetin diglucoside
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Flavonols Plant Flavonoids Metabolic Disease Phenols Polyphenols Brassica oleracea L. Extract Disease Research Fields Brassicaceae Extract
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Cat. No.: HY-W012956
CAS No.: 1072-83-9
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6-Hydroxybenzbromarone is the major metabolite of Benzbromarone with a longer half-life and greater pharmacological potency than the parent compound. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor with an IC50 value of 21.5 μM. 6-Hydroxybenzbromarone is an anti-angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting .
Cat. No.: HY-N0357
CAS No.: 873001-54-8
Category:
Triterpenes Plant Terpenoids Other Diseases Trichosanthes kirilowii Maxim. Extract Cucurbitaceae Extract Disease Research Fields
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Synonyms: 3-O-Caffeoylquinic acid (Standard); Heriguard (Standard); NSC-407296 (Standard)
Cat. No.: HY-N8796
CAS No.: 75679-58-2
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Research Areas:
2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone is a dihydrochalcone compound isolated from Iryanthera juruensis Warb. 2',4'-Dihydroxy-4,6'-diMethoxydihydrochalcone is a major cytotoxic metabolite when tested against a panel of cancer cell lines .
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Florfenicol amine hydrochloride is the major metabolite of Florfenicol (HY-B1374) and serves as a marker residue in studies of the in vivo disposition and residue depletion of Florfenicol. Florfenicol amine hydrochloride is eliminated more slowly than the parent compound and persists in plasma and tissues. Florfenicol amine hydrochloride is used in veterinary research for studies on the metabolism, pharmacokinetics, and residue depletion of Florfenicol .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
