1 Result for "

Mal-Exatecan

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Mal-Exatecan" in MCE Product Catalog:

Cat. No.: HY-159783
CAS No.: 3028213-52-4
Research Areas:  

Cancer

Mal-Exatecan is a maleimide (Mal)-modified Exatecan (HY-13631) and is a DNA topoisomerase I (topoisomerase I) inhibitor. Mal-Exatecan serves as a cytotoxic payload for antibody-drug conjugates (ADCs), conjugating to antibody cysteine residues via the maleimide group and releasing Exatecan within tumor cells to exert cytotoxic effects. Mal-Exatecan can be used for ADC construction and cancer-related research .
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