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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
Melanocytes
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "Melanocytes" in MCE Product Catalog:
25
25 Publications Verification
Synonyms: α-Melanocyte-Stimulating Hormone
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Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
25
25 Publications Verification
Cat. No.: HY-P0252A
CAS No.: 171869-93-5
Synonyms: α-Melanocyte-Stimulating Hormone TFA
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Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
2
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2
2
2 Cited Publications
ZT-12-037-01 is a STK19-targeted inhibitor, has a high-affinity interaction with STK19 protein and inhibits oncogenic NRAS-driven melanocyte malignant transformation. ZT-12-037-01 is an ATP-competitive inhibitor, inhibiting phosphorylation of NRAS (major isoform of Ras family) with an IC50 of 24 nM .
2
2 Cited Publications
Cat. No.: HY-N2438
CAS No.: 74805-91-7
Category:
Liliaceae Extract Other Flavonoids Asparagaceae Extract Plant Flavonoids Other Diseases Phenols Polyphenols Ophiopogon japonicus (L. f.) Ker Gawl. Extract Disease Research Fields
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2
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2
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McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 produces a significant inhibitory effect on Muscarine (HY-121404)-evoked catecholamine secretion from the isolated perfused rat adrenal gland. McN-A-343 is involved in the regulation of neuronal firing and activates enteroendocrine L cells to release glucagon-like peptide 1 (GLP-1) and modulates the secretion of α-melanocyte stimulating hormone (α-MSH) from the pituitary gland in the central nervous system. McN-A-343 reduces colonic inflammation and oxidative stress in Acetic acid (HY-Y0319)-induced ulcerative colitis (UC) mice. McN-A-343 can be used for the study of ulcerative colitis .
2
2 Cited Publications
Synonyms: Ordenina hydrochloride; Peyocactine hydrochloride
1
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Research Areas:
Metabolic Disease Inflammation/Immunology Endocrinology Cancer
Melanotan I (MT-I; [Nle4,D-Phe7]-α-MSH) is an α-MSH (HY-P0252) analog, synthetic melanotropic peptide, and melanocortin receptor (MCR) agonist. Melanotan I induces skin tanning by mimicking the action of α-MSH on the melanocortin 1 receptor (MC1R) in melanocytes. As an appetite suppressant, Melanotan I impairs the ability of insulin to inhibit endogenous glucose production, suppresses leptin secretion from adipose tissue, and thereby reduces voluntary feed intake in ewes. Melanotan I can be used in research related to UV-induced skin damage, polymorphic light eruption, ruminant feeding, and sexual dysfunction .
1
1 Cited Publications
Cat. No.: HY-P1531
CAS No.: 72629-65-3
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1
1 Cited Publications
Cat. No.: HY-N2466A
CAS No.: 1566590-77-9
Synonyms: MT-I acetate; [Nle4,D-Phe7]-α-MSH acetate
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Research Areas:
Metabolic Disease Inflammation/Immunology Endocrinology Cancer
Melanotan I (MT-I; [Nle4,D-Phe7]-α-MSH) acetate is an α-MSH (HY-P0252) analog, synthetic melanotropic peptide, and melanocortin receptor (MCR) agonist. Melanotan I acetate induces skin tanning by mimicking the action of α-MSH on the melanocortin 1 receptor (MC1R) in melanocytes. As an appetite suppressant, Melanotan I acetate impairs the ability of insulin to inhibit endogenous glucose production, suppresses leptin secretion from adipose tissue, and thereby reduces voluntary feed intake in ewes. Melanotan I acetate can be used in research related to UV-induced skin damage, polymorphic light eruption, ruminant feeding, and sexual dysfunction .
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Tyrosinase (EC 1.14.18.1) (Polyphenol oxidase) is a rate-limiting enzyme that controls the production of melanin. Tyrosinase is mainly found in melanosomes synthesized by skin melanocytes. Tyrosinase can be used in research on Parkinson's disease, melanoma and pigmentation .
Cat. No.: HY-P3452
CAS No.: 1036207-61-0
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Cat. No.: HY-P3662
CAS No.: 82188-67-8
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Cat. No.: HY-P2506
CAS No.: 212370-36-0
Synonyms: Mgp100 (25-33)
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Cat. No.: HY-135014
CAS No.: 175357-18-3
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Undecylenoyl phenylalanine is an antagonist for α-melanocyte-stimulating hormone (MSH) and β-adrenergic receptor (β-ADR) to reduce the melanogenesis in melanocytes, reduces hyperpigmentation and thus ameliorates melasma lesions and solar lentigines .
Cat. No.: HY-P1504
CAS No.: 17908-57-5
Synonyms: Beta-MSH (1-22) (human)
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Cat. No.: HY-P1504A
Synonyms: Beta-MSH (1-22) (human) TFA
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Cat. No.: HY-P99622
CAS No.: 1188277-05-5
Synonyms: IMC-20D7S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
