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430 Results for "

Membrane disruption

" in MedChemExpress (MCE) Product Catalog:

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Amphotericin B

34 Publications Verification

Cat. No.: HY-B0221

CAS No.: 1397-89-3

Category:

Infection Microorganisms Ketones, Aldehydes, Acids Disease Research Fields

Target:

Fungal Antibiotic Bacterial Parasite

Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.

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L-Leucyl-L-Leucine methyl ester hydrochloride

22 Cited Publications

Cat. No.: HY-129905

CAS No.: 6491-83-4

Purity: 98.92%

Synonyms: LLOMe hydrochloride; Leu-Leu methyl ester hydrochloride; H-Leu-Leu-OMe hydrochloride

Category:

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Apoptosis Caspase

L-Leucyl-L-Leucine methyl ester (LLOMe; Leu-Leu methyl ester; H-Leu-Leu-OMe) hydrochloride is a lysosomal disrupting agent and apoptosis inducer that, through receptor-mediated endocytosis and lysosomal dipeptidyl peptidase I conversion, induces caspase activation, lysosomal membrane permeabilization, and DNA fragmentation, and requires cathepsin C to exert membrane-lytic activity, thereby selectively killing natural killer cells. L-Leucyl-L-Leucine methyl ester hydrochloride can be used for research related to lysosomal function and apoptosis .

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L-Leucyl-L-Leucine methyl ester hydrobromide

22 Cited Publications

Cat. No.: HY-129905A

CAS No.: 16689-14-8

Purity: 99.69%

Synonyms: LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide

Category:

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Apoptosis Caspase

L-Leucyl-L-Leucine methyl ester (LLOMe; Leu-Leu methyl ester; H-Leu-Leu-OMe) hydrobromide is a lysosomal disrupting agent and apoptosis inducer that, through receptor-mediated endocytosis and lysosomal dipeptidyl peptidase I conversion, induces caspase activation, lysosomal membrane permeabilization, and DNA fragmentation, and requires cathepsin C to exert membrane-lytic activity, thereby selectively killing natural killer cells. L-Leucyl-L-Leucine methyl ester hydrobromide can be used for research related to lysosomal function and apoptosis .

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Zinc Pyrithione

13 Cited Publications

Cat. No.: HY-B0572

CAS No.: 13463-41-7

Target:

Environmental Pollutants Bacterial Cuproptosis Proton Pump Fungal

Research Areas:

Infection Metabolic Disease

Zinc Pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump . Zinc Pyrithione is also a copper ionophore that delivers copper into cells and is a useful tool for studying cuproptosis .

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