47 Results for "

Michael addition

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "Michael addition" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-166648
Target:  

Liposome

Research Areas:  

Cancer

DSPE-PEG2000-Maleimide sodium (purity>98%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>98%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>98%) is applicable to research on drug delivery .
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4
4 Cited Publications
Cat. No.: HY-166648A
Target:  

Liposome

Research Areas:  

Others

DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
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Cat. No.: HY-Y0232
CAS No.: 2033-24-1
Synonyms: 2,2-Dimethyl-1,3-dioxane-4,6-dione
Meldrum's acid (2,2-Dimethyl-1,3-dioxane-4,6-dione) is a nucleophilic reagent. Meldrum's acid participates in Michael addition reactions. Meldrum's acid can be used in asymmetric organocatalysis .
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Cat. No.: HY-W039953
CAS No.: 98924-81-3
Synonyms: N-azidoacetylglucosamine-tetraacylated
Research Areas:  

Infection

Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-containing fully acetylated N-acetylglucosamine analog, a metabolic glycan marker, and also an inducer of S-glycosylation. Ac4GlcNAz can be taken up by bacteria, processed via endogenous carbohydrate biosynthesis pathways, and integrated into glycans by replacing natural monosaccharides. Under alkali promotion, Ac4GlcNAz undergoes β-elimination to form α,β-unsaturated aldehydes, which then bind to cysteine residues via Michael addition. Ac4GlcNAz can be integrated into glycoproteins. Ac4GlcNAz is applicable to research related to Helicobacter pylori infection .
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Cat. No.: HY-P4566
CAS No.: 52899-09-9
Synonyms: Pro-Val
Target:  

Dipeptidyl Peptidase

Research Areas:  

Others

H-Pro-Val-OH is a deprotonation dipeptide containing proline, which can catalyze the Michael addition reaction of acetone to trans-β-nitrostyrene. H-Pro Val OH can also serve as a substrate for fibroblast enzymes and prolinase, and has potential applications in biochemical analysis .
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Cat. No.: HY-W591476B
CAS No.: 134874-49-0
Synonyms: mPEG750-SH
m-PEG750-thiol (mPEG750-SH) is a thiolated methoxypolyethylene glycol oligomer. m-PEG750-thiol serves for the synthesis of gold nanorods (AuNR) and also acts as a side chain fragment precursor for post-polymerization Michael addition reactions. m-PEG750-thiol can be used in organic synthesis-related research .
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Cat. No.: HY-113053
CAS No.: 14152-28-4
Purity:  98%
Prostaglandin A1 is a dehydrated derivative of Prostaglandin E1. Prostaglandin A1 exhibits antiviral, anti-inflammatory, antitumor, neuroprotective, and antihypertensive activities. Prostaglandin A1 covalently binds to cysteine residues of target proteins through Michael addition, or activates pathways such as PPARγ and HSPs via transcriptional regulation. Prostaglandin A1 is used in research on Mayaro virus infection, stroke, Alzheimer's disease, neuroblastoma, melanoma, and severe gestational hypertension .
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Cat. No.: HY-W190755
CAS No.: 87135-00-0
Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
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Cat. No.: HY-W190746
CAS No.: 123687-40-1
Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
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Cat. No.: HY-174941
Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
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Cat. No.: HY-183387
CAS No.: 1348565-08-1
Target:  

Parasite Cathepsin

Research Areas:  

Infection

K11002 hydrobromide is a cysteine protease inhibitor. K11002 hydrobromide forms a covalent bond with the active site cysteine residue via Michael addition. K11002 hydrobromide inhibits the growth of Trypanosoma brucei. K11002 hydrobromide can be used in the research of African human trypanosomiasis (sleeping sickness) .
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Cat. No.: HY-W1052227
DMPE-PEG2000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1052492
Target:  

Liposome

Research Areas:  

Others

DPPE-PEG2000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183126
Target:  

Liposome

Research Areas:  

Others

DSG-PEG1000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG1000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183126A
Target:  

Liposome

Research Areas:  

Others

DSG-PEG2000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183126B
Target:  

Liposome

Research Areas:  

Others

DSG-PEG3400-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183126C
Target:  

Liposome

Research Areas:  

Others

DSG-PEG5000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-183126D
Target:  

Liposome

Research Areas:  

Others

DSG-PEG10000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG10000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1052227A
DMPE-PEG3400-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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Cat. No.: HY-W1052227B
DMPE-PEG5000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
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