213

Z-VAD(OMe)-FMK

213 Publications Verification

Cat. No.: HY-16658

CAS No.: 187389-52-2

Synonyms: Z-Val-Ala-Asp(OMe)-FMK

Target:

Caspase

Research Areas:

Cancer

Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor . Z-VAD(OMe)-FMK is an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor. Z-VAD(OMe)-FMK irreversibly modifies UCHL1 by targeting the active site of UCHL1 .

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59

Thiamet G

59 Cited Publications

Cat. No.: HY-12588

CAS No.: 1009816-48-1

Purity: 99.99%

Target:

OGA Autophagy

Research Areas:

Cancer

Thiamet G is a potent and selective inhibitor of O-GlcNAcase (OGA), which acts to remove O-GlcNAc from modified proteins, with K_i of 20 nM for human OGA.

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52

N-Ethylmaleimide

52 Cited Publications

Cat. No.: HY-D0843

CAS No.: 128-53-0

Synonyms: NEM

Target:

Cathepsin Deubiquitinase Apoptosis

Research Areas:

Infection Inflammation/Immunology

N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC₅₀ value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .

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21

Leflunomide

21 Cited Publications

Cat. No.: HY-B0083

CAS No.: 75706-12-6

Synonyms: HWA486; RS-34821; SU101

Target:

Dihydroorotate Dehydrogenase Bacterial

Research Areas:

Cancer

Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent.

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21

DOTAP chloride

21 Cited Publications

Cat. No.: HY-112754A

CAS No.: 132172-61-3

Purity: 99.91%

Synonyms: 1,2-Dioleoyl-3-trimethylammonium-propane chloride

Target:

Liposome

Research Areas:

Others

DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .

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16

MicroRNA Inhibitor Negative Control

16 Cited Publications

Cat. No.: HY-RI04602

Target:

MicroRNA

Research Areas:

Others

MicroRNA Inhibitor Negative Control is a full-length nucleotide 2'-methoxy modified oligonucleotide, and can be used as a negative control. The sequence of MicroRNA Inhibitor Negative Control is derived from cel-mir-239b. It has minimal sequence identity with miRNAs in human, mouse, and rat.

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12

DMEM (High Glucose, L-Glutamine, Pyruvate, Phenol Red, no HEPES)

12 Cited Publications

Cat. No.: HY-K3001

DMEM (Dulbecco's Modified Eagle Medium) is a widely used basal medium for supporting the growth of many different mammalian cells. Cell lines successfully cultured in DMEM include Hela, 293, Cos-7, and PC-12, as well as primary fibroblasts, neurons, glial cells, HUVECs, and smooth muscle cells. The 500 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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8

N6-Methyladenosine

8 Cited Publications

Cat. No.: HY-N0086

CAS No.: 1867-73-8

Synonyms: 6-Methyladenosine; N-Methyladenosine

Category:

Infection Natural Products Microorganisms Endogenous metabolite Disease Research Fields

Target:

Influenza Virus Endogenous Metabolite

N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.

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8

DMEM/F-12 (1:1), L-Glutamine, Phenol Red, HEPES

8 Cited Publications

Cat. No.: HY-K3002

DMEM/F-12 (Dulbecco's Modified Eagle Medium/Nutrient Mixture F-12) is a widely used basal medium for supporting the growth of many different mammalian cells. Cell successfully cultured in DMEM/F-12 include MDCK, glial cells, fibroblasts, human endothelial cells, etc. The 500 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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