3907 Results for "

Mutant Strains RSV

" in MedChemExpress (MCE) Product Catalog:

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214

Osimertinib dimesylate

214 Publications Verification

Cat. No.: HY-79077

CAS No.: 2070014-82-1

Synonyms: AZD-9291 dimesylate; Mereletinib dimesylate

Target:

EGFR

Research Areas:

Cancer

Osimertinib dimesylate (AZD-9291 dimesylate) is an irreversible and mutant selective EGFR inhibitor with IC₅₀s of 12 and 1 nM against EGFR ^L858R and EGFR ^L858R/T790M, respectively.

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214

Osimertinib

214 Publications Verification

Cat. No.: HY-15772

CAS No.: 1421373-65-0

Purity: 99.92%

Synonyms: AZD-9291; Mereletinib

Target:

EGFR

Research Areas:

Cancer

Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC₅₀ of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer .

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214

Osimertinib mesylate

214 Publications Verification

Cat. No.: HY-15772A

CAS No.: 1421373-66-1

Purity: 99.97%

Synonyms: AZD-9291 mesylate; Mereletinib mesylate

Target:

EGFR

Research Areas:

Cancer

Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC₅₀ of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer .

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Exendin-4

72 Cited Publications

Cat. No.: HY-13443

CAS No.: 141758-74-9

Purity: 99.95%

Synonyms: Exenatide

Target:

GLP Receptor Apoptosis

Research Areas:

Cardiovascular Disease Metabolic Disease

Exendin‑4 (Exenatide) is an orally active, blood-brain barrier-permeable glucagon-like peptide-1 receptor (GLP‑1 receptor) agonist that resists degradation mediated by dipeptidyl peptidase IV. Exendin‑4 mediates multiple glucose-regulating effects, including stimulation of glucose-dependent insulin secretion, inhibition of glucagon production, increase in β-cell mass, delay of gastric emptying, reduction of food intake, improvement of peripheral insulin sensitivity, and restoration of normal islet structure. Exendin‑4 inhibits oxidative stress, alleviates inflammatory responses, and reduces neuronal apoptosis. Exendin‑4 reduces the aggregation level of mutant huntingtin, improves motor function, prolongs survival time, and regulates the expression levels of leptin and ghrelin. Exendin‑4 can be used in research related to type 2 diabetes, acute ischemic stroke, and Huntington's disease .

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Exendin-4 acetate

72 Cited Publications

Cat. No.: HY-13443A

CAS No.: 914454-01-6

Purity: 99.91%

Synonyms: Exenatide acetate

Target:

GLP Receptor Apoptosis

Research Areas:

Cardiovascular Disease Metabolic Disease

Exendin-4 acetate (Exenatide acetate) is an orally active, blood-brain barrier-permeable glucagon-like peptide-1 receptor (GLP‑1 receptor) agonist that resists degradation mediated by dipeptidyl peptidase IV. Exendin-4 acetate mediates multiple glucose-regulating effects, including stimulation of glucose-dependent insulin secretion, inhibition of glucagon production, increase in β-cell mass, delay of gastric emptying, reduction of food intake, improvement of peripheral insulin sensitivity, and restoration of normal islet structure. Exendin-4 acetate inhibits oxidative stress, alleviates inflammatory responses, and reduces neuronal apoptosis. Exendin-4 acetate reduces the aggregation level of mutant huntingtin, improves motor function, prolongs survival time, and regulates the expression levels of leptin and ghrelin. Exendin-4 acetate can be used in research related to type 2 diabetes, acute ischemic stroke, and Huntington's disease .

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Gentamicin

71 Cited Publications

Cat. No.: HY-A0276A

CAS No.: 1403-66-3

Target:

Environmental Pollutants Antibiotic Bacterial

Research Areas:

Infection Cancer

Gentamicin, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin inhibits DNase I with an IC₅₀ of 0.57 mM .

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Gentamicin sulfate

71 Cited Publications

Cat. No.: HY-A0276

CAS No.: 1405-41-0

Category:

Disease Research Antibacterial Other Antibiotics Plant agriculture research Infection Microorganisms Plant Cell Culture Antibiotics Resistance Selection Animal Husbandry Mammalian Cell Culture Disease Research Fields

Target:

Environmental Pollutants Antibiotic Bacterial

Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC₅₀ of 0.57 mM .

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Celastrol

69 Cited Publications

Cat. No.: HY-13067

CAS No.: 34157-83-0

Purity: 99.64%

Synonyms: Tripterine; Tripterin

Category:

Triterpenes Anti-aging Celastraceae Extract Terpenoids Plants 500 - Internal Server Error | MedChemExpress

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