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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
N13
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "N13" in MCE Product Catalog:
Cat. No.: HY-W754950
Synonyms: N-(1,3-Dimethylbutyl)-N'-phenyl-1,4-phenylenediamine-d5
Cat. No.: HY-B2130S
CAS No.: 2421217-23-2
Uric acid- 13C, 15N3 is the 15N, 13C-labeled Uric acid (HY-B2130). Uric acid is an orally active oxygen free radical scavenger that helps maintain stable blood pressure and combat oxidative stress. Uric acid can scavenge ROS, such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation. Uric acid can be used as a modeling agent in research on hyperuricemia-induced hypertension models .
Cat. No.: HY-W012340S
CAS No.: 2483830-23-3
Synonyms: L-Homoarginine-13C7,15N4 hydrochloride
H-HomoArg-OH- 13C7, 15N4 hydrochloride (L-Homoarginine- 13C7, 15N4 hydrochloride) is the 15N, 13C-labeled H-HomoArg-OH (hydrochloride) (HY-W012340). H-HomoArg-OH hydrochloride (L-Homoarginine hydrochloride) is an orally active endogenous non-protein amino acid. H-HomoArg-OH hydrochloride acts as a weak alternative substrate for NOS and interferes with NO production, selectively inhibits tissue-nonspecific alkaline phosphatase (TNAP), and suppresses the uptake of arginine by y +-type transporters (system y +). H-HomoArg-OH hydrochloride increases tissue hArg concentrations in vivo, regulates amino acid homeostasis, and improves renal function and pathological features of diabetic nephropathy. H-HomoArg-OH hydrochloride can be used in studies related to diabetes and cardiomyopathy .
Cat. No.: HY-N0666S1
CAS No.: 202468-27-7
Cat. No.: HY-10984S3
Synonyms: CC-4047-15N,13C5
Cat. No.: HY-B0150S1
CAS No.: 2117346-85-5
Synonyms: Niacinamide-15N,13C3; Nicotinic acid amide-15N,13C3
Cat. No.: HY-W021448S1
CAS No.: 2483829-93-0
Synonyms: Guanidinoacetic acid-15N,13C2
Cat. No.: HY-16637S4
CAS No.: 2687960-47-8
Synonyms: Vitamin B9-13C5,15N; Vitamin M-13C5,15N
Cat. No.: HY-P1032S2
Research Areas:
Cat. No.: HY-B0143S4
CAS No.: 2483829-87-2
Cat. No.: HY-W008848S
CAS No.: 2483830-16-4
Cat. No.: HY-40354S1
Synonyms: Tasocitinib-13C3,15N; CP-690550-13C3,15N
Target:
Tofacitinib- 13C3, 15N (Tasocitinib- 13C3, 15N; CP-690550- 13C3, 15N) is the 15N, 13C-labeled Tofacitinib (HY-40354). Tofacitinib (Tasocitinib) is an orally active, blood-brain barrier permeable selective inhibitor of JAK1/JAK3. Tofacitinib blocks the JAK-STAT/NF-κB signaling pathway, inhibits cytokine signal transduction, phosphorylation of STAT1/STAT5, and suppresses innate and adaptive immune responses. Tofacitinib can be used in research related to major depressive disorder, rheumatoid arthritis, pulmonary diseases, systemic lupus erythematosus, and immune-mediated liver injury .
Cat. No.: HY-B0178AS
CAS No.: 285977-73-3
Synonyms: Guanidinium-13C,15N3 chloride; Aminoformamidine-13C,15N3 hydrochloride
Cat. No.: HY-B0101S1
CAS No.: 1309935-84-9
Synonyms: UK-49858-13C2,15N
Cat. No.: HY-113225S1
Synonyms: GTP-13C10,15N5 tetraammonium
Research Areas:
Guanosine triphosphate- 13C10, 15N5 tetraammonium solution (100 mM) (GTP- 13C10, 15N5 tetraammonium) is the 15N, 13C-labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate (GTP) is a critical nucleotide and regulator of cellular metabolism. Guanosine triphosphate promotes ribosomal DNA localization, pre-rRNA transcription and ribosome biogenesis by binding to RNA polymerase I and GPN proteins (GPN1/3). Guanosine triphosphate links MYC-dependent ribosome biogenesis to nucleotide sufficiency, acts as a metabolic gatekeeper supporting protein synthesis, DNA/RNA synthesis and cellular signal transduction, while also participating in the physiological activities of pancreatic β-cells and serving as an oxidative substrate for reactive oxygen species. In small cell lung cancer with high MYC expression, Guanosine triphosphate accumulates through the IMPDH-driven synthetic pathway, thereby affecting apoptosis and mitotic processes. Guanosine triphosphate is used in the research of small cell lung cancer, hepatoblastoma and cellular metabolism .
Cat. No.: HY-10019S1
Synonyms: CP 526555-15N,13C,d2
Cat. No.: HY-W750551
CAS No.: 285978-24-7
Cat. No.: HY-W722122
Synonyms: N-(1-((3r,5r,7r)-Adamantan-1-yl)ethyl)hydroxylamine-d4
Cat. No.: HY-N0666S7
CAS No.: 2483830-03-9
Cat. No.: HY-P810460
Synonyms: Rab9 Effector Protein With Kelch Motifs, RAB9P40, BA65N13.1, 40 KDa Rab9 Effector Protein, P40, Rab9 Effector P40
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
