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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
NJT-12
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "NJT-12" in MCE Product Catalog:
Cat. No.: HY-189903
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NJT-12 is a PARP-1 and CK2α inhibitor with IC50 values of 3.40 nM and 4.31 nM, respectively. NJT-12 blocks DNA single-strand break repair, promotes DNA damage, and interferes with tumor stemness signaling by inhibiting CK2α-mediated substrate phosphorylation. NJT-12 induces apoptosis through caspase signaling and G2-M phase arrest, inhibits migration and invasion, and reverses epithelial-mesenchymal transition. NJT-12 inhibits tumor growth in xenograft models with a favorable biosafety profile. NJT-12 can be used for research on ovarian cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
