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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
NP cells
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "NP cells" in MCE Product Catalog:
19
13
13 Cited Publications
Cat. No.: HY-W013523
CAS No.: 65182-56-1
2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells .
12
Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex . Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis (IC90=37 nM) . Zotatifin induces cell apoptosis .
4
4 Cited Publications
Cat. No.: HY-P1408
CAS No.: 404882-00-4
4
4 Cited Publications
Research Areas:
MitoTEMPOL is a mitochondria-targeted superoxide scavenger. MitoTEMPOL accumulates in mitochondria via membrane potential and locally scavenges superoxide anions. MitoTEMPOL alleviates hepatic oxidative stress and alterations in genes related to autophagy in STZ (HY-13753)-induced diabetic models. MitoTEMPOL inhibits diaphragmatic mitochondrial dysfunction and activation of proteolytic pathways in sepsis models. MitoTEMPOL also alleviates AGEs (HY-NP165)-induced ferritinophagy-dependent ferroptosis in human umbilical vein endothelial cells. MitoTEMPOL is used in research related to diabetes, sepsis, and vascular endothelial ferroptosis .
2
2
Category:
Plant Coumarins Phenylpropanoids Other Families Extract Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Cat. No.: HY-NP141
Synonyms: 4-Hydroxy-3-nitrophenylacetyl-bovine serum albumin
Cat. No.: HY-NP137
Cat. No.: HY-W019724
CAS No.: 563-96-2
Cat. No.: HY-163159
CAS No.: 2409825-32-5
Research Areas:
NP3-562 is an orally active NLRP3 Inhibitor. NP3-562 inhibits IL-1β release in the supernatant of Nigericin (HY-127019)-stimulated THP-1 cells (IC50 = 66 nM), human whole blood (IC50 = 214 nM) and a mouse acute peritonitis model. NP3-562 can be used for the study of acute peritonitis .
Cat. No.: HY-P1066
CAS No.: 217082-57-0
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Cat. No.: HY-W004570
CAS No.: 4199-88-6
Synonyms: 5-NP
Target:
Cat. No.: HY-P1064
CAS No.: 252642-12-9
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Cat. No.: HY-P1065
CAS No.: 230299-95-3
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Cat. No.: HY-NP188
Synonyms: LEL (FITC)
Cat. No.: HY-N4184
CAS No.: 91433-17-9
Cat. No.: HY-B1735
CAS No.: 32828-81-2
Target:
Picotamide is an orally active TXA2 receptor and TXA2 synthase inhibitor. Picotamide inhibits ADP (HY-W010918)-, Arachidonic acid (HY-109590)-, and Collagen (HY-NP003)-induced platelet aggregation, reduces TXA2 production during coagulation, and does not inhibit PGI2 synthesis in endothelial cells. Picotamide inhibits contractions induced by α1-adrenergic receptor agonism, TXA2 mediation, and neurogenic (electrical field stimulation-induced) factors in human prostatic smooth muscle, and broadly inhibits agonist-induced contractions of porcine interlobar renal and coronary arteries. Picotamide can be used in research related to thromboembolic diseases, atherosclerosis, and lower urinary tract symptoms .
Cat. No.: HY-P1064A
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Cat. No.: HY-N12110
CAS No.: 10371-86-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
