19 Results for "

NaV1.3

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "NaV1.3" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-16787
CAS No.: 313254-51-2
Target:  

Sodium Channel

Research Areas:  

Cardiovascular Disease

ICA-121431 is a nanomolar potent and broad-spectrum voltage-gated sodium channel (Nav) blocker, shows equipotent selectivity for human Nav1.1 and Nav1.3 subtypes with IC50 values of 13 nM and 23 nM, respectively. ICA-121431 shows less potent inhibition of Nav1.2 (IC50=240 nM) and 1,000 fold selectivity against Nav1.4, Nav1.6, and the TTX-resistant human Nav1.5 and Nav1.8 channels (IC50s >10 μM).
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Cat. No.: HY-N1847
CAS No.: 21913-98-4
Category:  

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