547 Results for "

Naturally

" in MedChemExpress (MCE) Product Catalog:
Products (547)

547 Results for "Naturally" in MCE Product Catalog:

414
Paclitaxel
Paclitaxel
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414 Publications Verification
Cat. No.: HY-B0015
CAS No.: 33069-62-4
Category:  

Taxaceae Extract Terpenoids Diterpenoids Plants Disease Research Fields Cancer Taxus chinensis (Pilger) Rehd.

Target:  

Microtubule/Tubulin ADC Payloads Apoptosis Autophagy

Paclitaxel is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy .
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65
D-Glucose
D-Glucose
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65 Cited Publications
Cat. No.: HY-B0389
CAS No.: 50-99-7
Synonyms: Glucose; D-(+)-Glucose; Dextrose
Category:  

Metabolic Disease Endogenous metabolite Disease Research Fields Sweeteners Saccharides Food Research Monosaccharides

Target:  

Environmental Pollutants Endogenous Metabolite

D-Glucose is the naturally occurring form of glucose and the most abundant monosaccharide. D-Glucose is a critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic or abiotic stress response .
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29
Vitamin D3
Vitamin D3
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29 Cited Publications
Cat. No.: HY-15398
CAS No.: 67-97-0
Purity:  99.94%
Synonyms: Cholecalciferol; Colecalciferol
Category:  

Human Gut Microbiota Metabolites Natural Products Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields Cancer

Target:  

Environmental Pollutants Endogenous Metabolite Bacterial VD/VDR

Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
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26
Piceatannol
Piceatannol
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26 Cited Publications
Cat. No.: HY-13518
CAS No.: 10083-24-6
Purity:  98.97%
Synonyms: Astringenin; trans-Piceatannol
Category:  

Microorganisms Rheum palmatum L. Stilbenes Plants Disease Research Fields Polygonaceae Extract Cancer

Target:  

Syk Autophagy Apoptosis Endogenous Metabolite

Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI) . Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties . Piceatannol induces apoptosis in DLBCL cell lines . Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells .
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25
α-Vitamin E
α-Vitamin E
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25 Cited Publications
Cat. No.: HY-N0683
CAS No.: 59-02-9
Synonyms: (+)-α-Tocopherol; D-α-Tocopherol
Category:  

Infection Monophenols Moisture Phenols Cosmetic Research Endogenous metabolite Disease Research Fields Cancer Food Research

Target:  

Environmental Pollutants Reactive Oxygen Species (ROS) Endogenous Metabolite Ferroptosis Bacterial Influenza Virus

α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .
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25
Wogonin
Wogonin
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25 Cited Publications
Cat. No.: HY-N0400
CAS No.: 632-85-9
Category:  

Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Medicago truncatula Gaertn. Inflammation/Immunology Labiatae Extract

Target:  

CDK Wnt Autophagy Apoptosis

Wogonin is a naturally occurring mono-flavonoid, can inhibit the activity of CDK8 and Wnt, and exhibits anti-inflammatory and anti-tumor effects.
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21
Lycopene
Lycopene
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21 Cited Publications
Cat. No.: HY-N0287
CAS No.: 502-65-8
Category:  

Natural Products Endocrine diseases Solanum lycopersicum L. Plants Endogenous metabolite Solanaceae Extract Food Research Infection Human Gut Microbiota Metabolites Immune System Disorder Disease markers Pigments Disease Research Fields Cancer

Target:  

Reactive Oxygen Species (ROS) Endogenous Metabolite

Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects.
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19
Cytosporone B
Cytosporone B
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19 Cited Publications
Cat. No.: HY-N2148
CAS No.: 321661-62-5
Synonyms: Csn-B; Dothiorelone G
Category:  

Microorganisms Phenols Polyphenols Disease Research Fields Cancer

Target:  

Nuclear Hormone Receptor 4A/NR4A

Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM.
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17
Biochanin A
Biochanin A
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17 Cited Publications
Cat. No.: HY-14595
CAS No.: 491-80-5
Purity:  99.29%
Synonyms: 4-Methylgenistein; Olmelin
Category:  

Neurological Disease Leguminosae Extract Plants Trifolium pratense Linn. Flavonoids Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Cancer Isoflavones

Target:  

FAAH Autophagy Endogenous Metabolite

Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.
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16
Crustecdysone
Crustecdysone
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16 Cited Publications
Cat. No.: HY-N6979
CAS No.: 5289-74-7
Synonyms: 20-Hydroxyecdysone
Category:  

Cardiovascular Disease Animals Plants Compositae Extract Other Families Extract Endogenous metabolite Disease Research Fields Canavalia gladiata (Jacq.) DC. Steroids

Target:  

Caspase Autophagy Endogenous Metabolite

Crustecdysone (20-Hydroxyecdysone) is a naturally occurring ecdysteroid hormone isolated from Serratula coronata which controls the ecdysis (moulting) and metamorphosis of arthropods, it inhibits caspase activity and induces autophagy via the 20E nuclear receptor complex, EcR-USP . Crustecdysone exhibits regulatory or protective roles in the cardiovascular system . Crustecdysone is an active metabolite of Ecdysone (HY-N0179) .
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15
Deguelin
Deguelin
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15 Cited Publications
Cat. No.: HY-13425
CAS No.: 522-17-8
Purity:  99.20%
Synonyms: (-)-Deguelin; (-)-cis-Deguelin
Category:  

Flavonoids Isoflavanones Derris trifoliata Lour. Leguminosae Extract Plants Disease Research Fields Biological Pesticide Research Cancer Agricultural Research

Target:  

Akt Autophagy Apoptosis

Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB.
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14
β-Lapachone
β-Lapachone
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14 Cited Publications
Cat. No.: HY-13555
CAS No.: 4707-32-8
Purity:  99.93%
Synonyms: ARQ-501; NSC-26326
Category:  

Quinones Plants Other Families Extract Disease Research Fields Naphthalene Quinones Cancer

Target:  

Indoleamine 2,3-Dioxygenase (IDO) Topoisomerase Autophagy Apoptosis

β-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression.
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12
Selenomethionine
Selenomethionine
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12 Cited Publications
Cat. No.: HY-B1000
CAS No.: 1464-42-2
Synonyms: Seleno-DL-methionine; DL-Selenomethionine
Category:  

Microorganisms Disease markers Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer

Target:  

Autophagy Keap1-Nrf2

Selenomethionine is a naturally occurring amino acid containing selenium that has oral activity and is a common natural food source. Selenomethionine has antitumor activity .
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12
Hematoxylin
Hematoxylin
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12 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Category:  

Caesalpinia sappan L. Other Diseases Phenols Polyphenols Leguminosae Extract Plants Disease Research Fields

Target:  

Amyloid-β

Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
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12
Jasplakinolide
Jasplakinolide
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12 Cited Publications
Cat. No.: HY-P0027
CAS No.: 102396-24-7
Category:  

Antifungal Marine natural products Disease Research Other Antibiotics Infection Monophenols Animals Antibiotics Cyclopeptides Phenols Sponge Anticancer Disease Research Fields

Target:  

Arp2/3 Complex Fungal

Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a Kd of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .
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10
Clavulanic acid
Clavulanic acid
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10 Cited Publications
Cat. No.: HY-A0256
CAS No.: 58001-44-8
Target:  

Beta-lactamase Antibiotic Bacterial

Research Areas:  

Infection Inflammation/Immunology

Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias .
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10
3,4-Dicaffeoylquinic acid
3,4-Dicaffeoylquinic acid
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10 Cited Publications
Cat. No.: HY-N0057
CAS No.: 14534-61-3
Synonyms: 3,4-Di-O-caffeoylquinic acid; Isochlorogenic acid B
Category:  

Infection Ketones, Aldehydes, Acids Phenols Polyphenols Plants Caprifoliaceae Extract Endogenous metabolite Disease Research Fields

Target:  

Free Radical Scavengers Glycosidase Influenza Virus Apoptosis Endogenous Metabolite

3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL .
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10
Isoquercitrin
Isoquercitrin
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10 Cited Publications
Cat. No.: HY-N1445
CAS No.: 482-35-9
Synonyms: Isoquercetin; Quercetin 3-glucoside
Category:  

Flavonols Flavonoids Phenols Polyphenols Plants  Apocynum venetum Linn. Disease Research Fields Cancer Apocynaceae Extract

Target:  

NF-κB NO Synthase

Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway . Isoquercetin regulates the expression of nitric oxide synthase 2 (NO2) via modulating the nuclear factor-κB (NF-κB) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies .
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8
Vitamin K1
Vitamin K1
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8 Cited Publications
Cat. No.: HY-N0684
CAS No.: 84-80-0
Synonyms: Phylloquinone; Phytomenadione
Category:  

Cardiovascular Disease Quinones Human Gut Microbiota Metabolites Plants Other Families Extract Endogenous metabolite Disease Research Fields Naphthalene Quinones

Target:  

Others

Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
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8
Hypericin
Hypericin
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8 Cited Publications
Cat. No.: HY-N0453
CAS No.: 548-04-9
Category:  

Quinones Anthraquinones Guttiferae Extract Hyperlcurn perforatum L. Plants Disease Research Fields Cancer

Target:  

Apoptosis Influenza Virus Antibiotic Monoamine Oxidase PKC Cytochrome P450 Dopamine β-hydroxylase Reverse Transcriptase Telomerase

Hypericin is a naturally occurring substance found in Hyperlcurn perforatum L. Hypericin is an inhibitor of PKC (protein kinase C), MAO (monoaminoxidase), dopamine-beta-hydroxylase, reverse transcriptase, telomerase and CYP (cytochrome P450). Hypericin shows antitumor, antiviral, antidepressive activities, and can induce apoptosis .
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