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1 Cited Publications

Cat. No.: HY-119459

Purity: 99.30%

Target:

Environmental Pollutants Constitutive Androstane Receptor Parasite Caspase Fungal NF-κB Succinate Dehydrogenase Pregnane X Receptor (PXR)

Research Areas:

Infection Cancer

Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC₅₀ values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .

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Roridin A

Cat. No.: HY-N9599

CAS No.: 14729-29-4

Category:

Natural Products Microorganisms Other Diseases Disease Research Fields

Target:

Fungal Endogenous Metabolite Parasite Insecticide

Roridin A acts as an inhibitor of pollen development in Arabidopsis thaliana and nematicide. Roridin A is isolated from the fungus Cylindrocarpon sp. Roridin A delays the flowering time of Arabidopsis thaliana, inhibits pollen development and stem elongation, and blocks plant growth. Roridin A induces larval death of the southern root-knot nematode (Meloidogyne incognita) .

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Fluensulfone

Cat. No.: HY-107771

CAS No.: 318290-98-1

Purity: 99.52%

Synonyms: MCW-2

Target:

Parasite

Research Areas:

Cancer

Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.

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Chaetoglobosin A

Cat. No.: HY-N6744

CAS No.: 50335-03-0

Category:

Infection Alkaloids Human Gut Microbiota Metabolites Microorganisms Marine natural products Endogenous metabolite Disease Research Fields Marine microorganism Indole Alkaloids

Target:

Apoptosis Endogenous Metabolite Fungal Parasite Arp2/3 Complex

Chaetoglobosin A is a secondary metabolite and nematicide. Chaetoglobosin A is produced by Penicillium aquamarinium. Chaetoglobosin A targets Filamentous actin in cells, thereby inducing cell cycle arrest, and inhibiting membrane ruffle formation and cell migration. Chaetoglobosin A preferentially induces Apoptosis in chronic lymphocytic leukemia cells. Chaetoglobosin A induces dose- and time-dependent death in J2 larvae of the southern root-knot nematode (Meloidogyne incognita). Chaetoglobosin A can be used in studies related to root-knot nematode disease and chronic lymphocytic leukemia .

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Fluopyram (Standard)

Cat. No.: HY-119459R

CAS No.: 658066-35-4

Target:

Reference Standards Succinate Dehydrogenase Fungal Parasite Constitutive Androstane Receptor Caspase NF-κB

Research Areas:

Infection Cancer

Fluopyram (Standard) is the analytical standard of Fluopyram (HY-119459). This product is intended for research and analytical applications. Fluopyram is an orally active succinate dehydrogenase inhibitor, antifungal and nematicide. Fluopyram inhibits succinate dehydrogenase activity, activates CAR/PXR nuclear receptors, and increases caspase-3, TNF-α and NF-κB. Fluopyram inhibits the growth of F. virguliforme, Botrytis cinerea and Alternaria solani with EC₅₀ values of 3.35, 5.389 and 0.244 µg/mL, respectively. Fluopyram induces liver and thyroid tumor formation. Fluopyram is nephrotoxic and embryotoxic .

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