25 Results for "

Neuroprotectants

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "Neuroprotectants" in MCE Product Catalog:

2
Acetyl-L-carnitine hydrochloride
Acetyl-L-carnitine hydrochloride
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2 Cited Publications
Cat. No.: HY-B0762
CAS No.: 5080-50-2
Synonyms: O-Acetyl-L-carnitine hydrochloride; ALCAR hydrochloride
Category:  

Lipids Endogenous metabolite

Target:  

Caspase Apoptosis

Acetyl-L-carnitine (O-Acetyl-L-carnitine; ALCAR) hydrochloride is an orally active mitochondrial energy metabolism regulator and neuroprotectant that can penetrate the blood-brain barrier. Acetyl-L-carnitine hydrochloride selectively enters cells and the brain through the organic cation transporter OCTN2. Acetyl-L-carnitine hydrochloride can participate in fatty acid β-oxidation, promote acetylcholine synthesis, regulate mitochondrial function and inhibit oxidative stress as an acetyl donor. Acetyl-L-carnitine hydrochloride exerts its activity by enhancing energy metabolism, protecting neurons and improving synaptic plasticity. Acetyl-L-carnitine hydrochloride is mainly used in the study of neurodegenerative diseases and metabolic disorder-related diseases such as neonatal hypoxic-ischemic brain damage, Alzheimer's disease, and depression .
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Acetyl-L-carnitine
Acetyl-L-carnitine
0 Images
2 Cited Publications
Cat. No.: HY-113218
CAS No.: 3040-38-8
Purity:  ≥98.0%
Synonyms: O-Acetyl-L-carnitine; ALCAR
Category:  

Natural Products Animals

Target:  

Caspase Apoptosis

Acetyl-L-carnitine (O-Acetyl-L-carnitine; ALCAR) is an orally active mitochondrial energy metabolism regulator and neuroprotectant that can penetrate the blood-brain barrier. Acetyl-L-carnitine selectively enters cells and the brain through the organic cation transporter OCTN2. Acetyl-L-carnitine can participate in fatty acid β-oxidation, promote acetylcholine synthesis, regulate mitochondrial function and inhibit oxidative stress as an acetyl donor. Acetyl-L-carnitine exerts its activity by enhancing energy metabolism, protecting neurons and improving synaptic plasticity. Acetyl-L-carnitine is mainly used in the study of neurodegenerative diseases and metabolic disorder-related diseases such as neonatal hypoxic-ischemic brain damage, Alzheimer's disease, and depression .
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Pyridoxal
Pyridoxal
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1 Cited Publications
Cat. No.: HY-107469
CAS No.: 66-72-8
Purity:  99.61%
Synonyms: Pyridoxaldehyde
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite

Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS) .
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Pyridoxal (Standard)
Pyridoxal (Standard)
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1 Cited Publications
Cat. No.: HY-107469R
CAS No.: 66-72-8
Synonyms: Pyridoxaldehyde (Standard)
Category:  

Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite

Target:  

Endogenous Metabolite Reference Standards

Pyridoxal (Standard) is the analytical standard of Pyridoxal. This product is intended for research and analytical applications. Pyridoxal is a neuroprotectant. Pyridoxal is one of the main forms of vitamin B6. Pyridoxal is phosphorylated by pyridoxal kinase to pyridoxal phosphate (HY-B1744). Pyridoxal is oxidized by the liver to 4-pyridoxic acid (HY-113493) and excreted in the urine. Pyridoxal has shown promise in the study of carpal tunnel syndrome (CTS)[1][2][3].
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Aceglutamide
Aceglutamide
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Cat. No.: HY-B1065
CAS No.: 2490-97-3
Synonyms: α-N-Acetyl-L-glutamine; N2-Acetylglutamine
Category:  

Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Keap1-Nrf2 Akt ASK1 Apoptosis

Aceglutamide (α-N-Acetyl-L-glutamine; N2-Acetylglutamine) is a neuroprotectant that can penetrate the blood-brain barrier. Aceglutamide can enhance the antioxidant systems of glutathione (GSH), thioredoxin (Trx) and Nrf2. Aceglutamide also inhibits ASK1 and TRAF1, activates the Akt/Bcl-2 anti-apoptotic pathway, enhances the activity of antioxidant enzymes and reduces oxidative damage. Aceglutamide can improve neurological deficits after cerebral ischemia, reduce infarct volume, and inhibit neuronal apoptosis, especially substantia nigra dopaminergic neurons. Aceglutamide can reduce cerebral ischemia/reperfusion injury, improve motor dysfunction, and is used in ischemic stroke-related research .
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Capillarisin
Capillarisin
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Cat. No.: HY-121192
CAS No.: 56365-38-9
Purity:  99.27%
Category:  

Flavonoids Flavones Phenols Polyphenols Plants 500 - Internal Server Error | MedChemExpress

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