360 Results for "

Neurotransmitters

" in MedChemExpress (MCE) Product Catalog:
Products (360)

360 Results for "Neurotransmitters" in MCE Product Catalog:

52
52 Publications Verification
Cat. No.: HY-B1081
CAS No.: 28094-15-7
Synonyms: 6-Hydroxydopamine Hydrochloride
Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrochloride can be used for the research of Parkinson’s disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome .
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52
52 Publications Verification
Cat. No.: HY-B1081A
CAS No.: 636-00-0
Synonyms: 6-Hydroxydopamine hydrobromide; 6-OHDA hydrobromide
Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrobromide is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrobromide promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrobromide can be used for the research of Parkinson’s disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome .
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46
46 Cited Publications
Cat. No.: HY-B1473A
CAS No.: 50-67-9
Synonyms: 5-Hydroxytryptamine; 5-HT
Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
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46 Cited Publications
Cat. No.: HY-B1473
CAS No.: 153-98-0
Synonyms: 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride
Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist, with blood-brain barrier permeability. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
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44 Cited Publications
Cat. No.: HY-N0219
CAS No.: 485-49-4
Synonyms: (+)-Bicuculline
Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca 2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice .
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37 Cited Publications
Cat. No.: HY-N0304
CAS No.: 59-92-7
Synonyms: Levodopa; 3,4-Dihydroxyphenylalanine
L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease .
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37 Cited Publications
Cat. No.: HY-N0304A
CAS No.: 63302-01-2
Synonyms: Levodopa sodium; 3,4-Dihydroxyphenylalanine sodium
L-DOPA (Levodopa) sodium is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA sodium can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA sodium has anti-allodynic effects, and can be used for Parkinson's disease research .
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36
36 Cited Publications
Cat. No.: HY-P0201
CAS No.: 33507-63-0
Synonyms: Neurokinin P
Substance P (Neurokinin P) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
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36 Cited Publications
Cat. No.: HY-P0201A
CAS No.: 148470-19-3
Synonyms: Neurokinin P TFA
Substance P TFA (Neurokinin P TFA) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .
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35
35 Cited Publications
Cat. No.: HY-B0282
CAS No.: 60-31-1
Synonyms: ACh chloride
Acetylcholine (ACh) chloride, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) . Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro .
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35
35 Cited Publications
Cat. No.: HY-17551
CAS No.: 6384-92-5
Synonyms: N-Methyl-D-aspartic acid
NMDA is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.
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35
35 Cited Publications
Cat. No.: HY-101086
CAS No.: 2260-50-6
Purity:  98.59%
Synonyms: ACh iodide
Acetylcholine (ACh) iodide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine iodide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) . Acetylcholine iodide inhibits p53 mutant peptide aggregation in vitro .
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35 Cited Publications
Cat. No.: HY-B0282A
CAS No.: 66-23-9
Synonyms: ACh bromide
Acetylcholine (ACh) bromide, a neurotransmitter, is a potent cholinergic agonist. Acetylcholine bromide is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) . Acetylcholine bromide inhibits p53 mutant peptide aggregation in vitro .
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33
33 Cited Publications
Cat. No.: HY-B0451
CAS No.: 51-61-6
Synonyms: ASL279 free base
Dopamine is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine plays several important roles in the brain and body . Dopamine acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis .
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33
33 Cited Publications
Cat. No.: HY-B0451A
CAS No.: 62-31-7
Synonyms: ASL279
Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body . Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis .
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22 Cited Publications
Cat. No.: HY-A0129
CAS No.: 51-74-1
Synonyms: Histamine diphosphate
Histamine phosphate is the agonist for histamine receptor and a vasodilator. Histamine phosphate is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine phosphate affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine phosphate can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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22 Cited Publications
Cat. No.: HY-B0722
CAS No.: 56-92-8
Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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22 Cited Publications
Cat. No.: HY-B1204
CAS No.: 51-45-6
Synonyms: Ergamine
Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma .
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20
20 Cited Publications
Cat. No.: HY-14608
CAS No.: 56-86-0
Purity:  99.81%
L-Glutamic acid is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid can be used in the study of neurological diseases. L-Glutamic acid acts at ionotropic and metabotropic glutamate receptors .
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19
19 Cited Publications
Cat. No.: HY-14608A
CAS No.: 142-47-2
Purity:  ≥98.0%
L-Glutamic acid monosodium salt is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium salt has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium salt can be used in the study of neurological diseases. L-Glutamic acid monosodium salt acts at ionotropic and metabotropic glutamate receptors .
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