80

80 Publications Verification

Category:

Natural Products Plants Other Families Extract Disease Research Fields Cancer

Target:

Environmental Pollutants Apoptosis Autophagy Microtubule/Tubulin NOD-like Receptor (NLR)

Colchicine, an orally active alkaloid, is a potent tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC₅₀ of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs). Colchicine prevents non-steroidal anti-inflammatory drug (NSAID)-induced small intestinal injury by inhibiting activation of the NLRP3 inflammasome. Colchicine has extensive anti-inflammatory, immunosuppressive and strong anti-fibrosis effects and has the potential for gouty arthritis research .

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70

Celecoxib

70 Cited Publications

Cat. No.: HY-14398

CAS No.: 169590-42-5

Purity: 99.89%

Synonyms: SC 58635

Target:

COX

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Celecoxib,a selective and BBB-permeable non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor with an IC₅₀ of 40 nM.

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23

Ibuprofen sodium

23 Cited Publications

Cat. No.: HY-78131C

CAS No.: 31121-93-4

Synonyms: (±)-Ibuprofen sodium

Target:

COX Apoptosis Parasite

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Ibuprofen ((±)-Ibuprofen) sodium is an orally active, selective COX-1 inhibitor with an IC₅₀ value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .

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23

Ibuprofen

23 Cited Publications

Cat. No.: HY-78131

CAS No.: 15687-27-1

Synonyms: (±)-Ibuprofen

Target:

COX Apoptosis Parasite

Research Areas:

Infection Neurological Disease Inflammation/Immunology Cancer

Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC₅₀ value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .

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23

Ibuprofen L-lysine

23 Cited Publications

Cat. No.: HY-100586

CAS No.: 57469-77-9

Purity: 99.91%

Synonyms: (±)-Ibuprofen L-lysine

Target:

COX Apoptosis Parasite

Research Areas:

Infection Inflammation/Immunology Cancer

Ibuprofen ((±)-Ibuprofen) L-lysine is a potent orally active, selective COX-1 inhibitor with an IC₅₀ value of 13 μM. Ibuprofen L-lysine inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen L-lysine is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen L-lysine can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .

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21

Bicalutamide

21 Cited Publications

Cat. No.: HY-14249

CAS No.: 90357-06-5

Purity: 99.91%

Target:

Androgen Receptor Autophagy

Research Areas:

Cancer

Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer .

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