46 Results for "

Nucleophile

" in MedChemExpress (MCE) Product Catalog:
Products (46)

46 Results for "Nucleophile" in MCE Product Catalog:

3
LY2183240
LY2183240
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3 Cited Publications
Cat. No.: HY-10865
CAS No.: 874902-19-9
Purity:  98.01%
Target:  

FAAH Autophagy

Research Areas:  

Neurological Disease

LY2183240 is a highly potent blocker of anandamide uptake (IC50= 270 pM; Ki=540 nM). LY2183240 is a potent, covalent inhibitor of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) with an IC50 of 12.4 nM. LY2183240 inactivates FAAH by carbamylation of the enzyme's serine nucleophile. LY2183240 also inhibits several other brain serine hydrolases with IC50s of 5.3, 0.09, 8.2 nM for MAG lipase, bh6 and KIAA1363, respectively .
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2
α-Angelica lactone
α-Angelica lactone
0 Images
2 Cited Publications
Cat. No.: HY-N0548
CAS No.: 591-12-8
Category:  

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