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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
OBI
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "OBI" in MCE Product Catalog:
Synonyms: OBI-3424; TH-3424; (R)-AST-3424
Research Areas:
(R)-Odafosfamide (OBI-3424) is a proagent that is selectively converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent. (R)-Odafosfamide can be used for hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL) research .
Cat. No.: HY-168489
CAS No.: 3039487-10-7
Target:
Research Areas:
OBI-992 drug-linker is a drug-linker conjugate composed of the TOP I inhibitor Exatecan (HY-13631) and a linker. OBI-992 drug-linker can be used for the synthesis of the ADC OBI-992 .
Cat. No.: HY-164126
CAS No.: 1404341-58-7
6-O-Bis-(4,5-dimethoxy-2-nitrobenzyloxyphosphoryl)-D-trehalose is a synthetic compound that interferes with plant sugar signaling. After being absorbed by plants, 6-O-Bis-(4,5-dimethoxy-2-nitrobenzyloxyphosphoryl)-D-trehalose can trigger the release of T6P by light exposure, thereby activating the signaling pathway inside the plant. 6-O-Bis-(4,5-dimethoxy-2-nitrobenzyloxyphosphoryl)-D-trehalose can be used to study plant biosynthesis .
Cat. No.: HY-149040
CAS No.: 2097713-69-2
Synonyms: (S)-OBI-3424; (S)-TH-3424; AST-3424
Research Areas:
Odafosfamide ((S)-OBI-3424) is a highly selective prodrug bis-alkylating agent activated by aldehyde-keto reductase 1C3 (AKR1C3(). Odafosfamide is highly cytotoxic to cell lines with high AKR1C3 expression. Odafosfamide exhibits antitumor activity in a variety of tumors with high AKR1C3 expression (such as liver cancer, non-small cell lung cancer, and leukemia). Odafosfamide can be used in cancer research .
Cat. No.: HY-154424
CAS No.: 174221-86-4
Target:
Research Areas:
2′-Amino-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-RS09734
Target:
Research Areas:
OBI1 Human Pre-designed siRNA Set A contains three designed siRNAs for OBI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-164125
CAS No.: 1404341-61-2
Target:
Research Areas:
6-O-Bis[1-(2-nitrophenyl)-ethoxyphosphoryl]-D-trehalose is an important signaling molecule that regulates carbon utilization and growth in plants. 6-O-Bis[1-(2-nitrophenyl)-ethoxyphosphoryl]-D-trehalose releases T6P through light activation, which can stimulate starch synthesis and promote plant growth by inhibiting SnRK1, a protein kinase involved in energy conservation and survival. 6-O-Bis[1-(2-nitrophenyl)-ethoxyphosphoryl]-D-trehalose can be used to study plant growth and metabolism .
Cat. No.: HY-154198
CAS No.: 112897-99-1
Target:
Research Areas:
5′-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-154423
CAS No.: 177980-10-8
Target:
Research Areas:
2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2′-Azido-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-154298
CAS No.: 84138-86-3
Target:
Research Areas:
N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-W097775
CAS No.: 81352-25-2
Synonyms: 5'-O-(4,4'-DIMETHOXYTRITYL)ADENOSINE
Target:
Research Areas:
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) .
Cat. No.: HY-W854192
CAS No.: 196391-62-5
Target:
Research Areas:
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-N-[(dimethylamino)methylene]-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a phosphoramidite that can be used in the synthesis of oligonucleotides.
Cat. No.: HY-200335
CAS No.: 2382941-85-5
Target:
Research Areas:
Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-5-iodo-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a phosphoramidite that can be used in the synthesis of oligonucleotides.
Cat. No.: HY-200336
CAS No.: 1391914-08-1
Target:
Research Areas:
Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-5-bromo-2′-O-methyl-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a phosphoramidite that can be used in the synthesis of oligonucleotides.
Cat. No.: HY-W854193
CAS No.: 143060-53-1
Target:
Research Areas:
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-7,8-dihydro-N-(2-methyl-1-oxopropyl)-8-oxo-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
