41 Results for "

OC43

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "OC43" in MCE Product Catalog:

6
Vps34-IN-2
Vps34-IN-2
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6 Cited Publications
Cat. No.: HY-12473
CAS No.: 1523404-29-6
Purity:  99.81%
Target:  

PI3K SARS-CoV

Research Areas:  

Cancer

Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively . Vps34-IN-2 shows antiviral activity against SARS-CoV-2 (IC50 of 3.1 μM), HCoV-229E (IC50 of 0.7 μM) and HCoV-OC43 .
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Tubeimoside II
Tubeimoside II
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Cat. No.: HY-N0891
CAS No.: 115810-12-3
Synonyms: Tubeimoside-B
Category:  

Triterpenes Terpenoids Plants Other Families Extract Disease Research Fields Cancer

Target:  

EGFR TGF-β Receptor RIG-I-like receptor (RLR) SARS-CoV

Tubeimoside II is an orally active triterpenoid saponin and antiviral agent that binds to PACT/PRKRA with Kd values of 5.37 μM and 133.1 μM, respectively. Tubeimoside II inhibits oxidase-dependent EGFR activation and reduces TGF-β1-induced oxidative stress. Tubeimoside II activates the RIG-I signaling pathway and increases IFN-β secretion. Tubeimoside II suppresses TPA-induced ear edema, mouse sarcoma 180 growth, and TPA-induced skin tumor formation. Tubeimoside II exerts broad-spectrum antiviral activity against SARS-CoV-2, HCoV-OC43, and IAV-H1N1/FM1. Tubeimoside II can be used in research related to retinoblastoma, respiratory viral infections, skin tumors, and sarcoma 180 .
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2-Thiouridine
2-Thiouridine
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Cat. No.: HY-117813
CAS No.: 20235-78-3
Purity:  99.73%
Target:  

Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Dengue Virus Flavivirus CHIKV SARS-CoV

Research Areas:  

Infection

2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV) .
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Isocannflavin B
Isocannflavin B
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Cat. No.: HY-N12677
CAS No.: 199167-23-2
Synonyms: Caflanone; FBL-03G
Category:  

Flavonoids Flavones Pedaliaceae Extract 500 - Internal Server Error | MedChemExpress

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