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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
OPRD
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "OPRD" in MCE Product Catalog:
Cat. No.: HY-RS09801
Target:
Research Areas:
OPRD1 Human Pre-designed siRNA Set A contains three designed siRNAs for OPRD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-116163
CAS No.: 1565852-90-5
Synonyms: CYM50202
Target:
Research Areas:
ML350 (CYM50202) is a highly potent OPRK1 antagonist with selectivity and broad biological applications. With IC50 values of 9-16 nM, ML350 shows high selectivity for OPRK1, with selectivity of 219-382-fold and 20-35-fold relative to OPRD1 and OPRM1, respectively. ML350 exhibited favorable characteristics in in vivo pharmacokinetic analysis, including high passive membrane permeability and moderate human plasma protein binding. Extensive screening of ML350 against multiple ion channels, receptors, and transporters showed that it does not have adverse off-target effects .
Cat. No.: HY-W414109
CAS No.: 1172882-21-1
Target:
Research Areas:
ID110460002 possesses both full agonist activity at the μ-opioid receptor (OPRM) and agonist activity at the δ-opioid receptor (OPRD). ID110460002 acts as a potent agonist for the G protein pathways of both receptors, but exhibits only very weak partial agonist activity towards the β-arrestin-2 pathway. The agonistic potency of ID110460002 at OPRM has extremely high intrinsic activity and is unaffected by reduced receptor expression levels, while its potency at OPRD depends on receptor expression levels. ID110460002 displays tissue- or organ-dependent properties, and serves as a critical compound for investigating pain mechanisms and analgesia .
Cat. No.: HY-P702402
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: OPRD1; DOR; Opioid Receptor Delta 1; Opioid Receptor Delta 1 Isoform DOR-1E; OPRD; Opioid Receptor Delta 1 Isoform DOR-1B; Delta-Type Opioid Receptor; Opioid Receptor Delta 1 Isoform DOR-1C; D-OR-1; Opioid Receptor Delta 1 Isoform DOR-1D; DOR-1; Opioid Re
Species:
Human
Source:
E. coli Cell-free
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
