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6 Results for "

Osthole

" in MedChemExpress (MCE) Product Catalog:

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Osthole

21 Cited Publications

Cat. No.: HY-N0054

CAS No.: 484-12-8

Synonyms: Osthol; NSC 31868

Category:

Cardiovascular Disease Coumarins Plants Other Families Extract Biological Pesticide Research Agricultural Research Infection Phenylpropanoids Disease Research Fields Inflammation/Immunology Endocrinology

Target:

Histamine Receptor Apoptosis Parasite HBV

Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H₁ receptor activity. Osthole also suppresses the secretion of HBV in cells.

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NBM-T-BMX-OS01

Cat. No.: HY-176498

CAS No.: 1246952-34-0

Synonyms: BMX

Target:

VEGFR FAK Akt PERK AMPK Reactive Oxygen Species (ROS) Apoptosis

Research Areas:

Cardiovascular Disease Cancer

NBM-T-BMX-OS01 (BMX) is a derivative of Osthole (HY-N0054). NBM-T-BMX-OS01 attenuates the phosphorylation levels of ERK and Akt in an AMPK-dependent manner. NBM-T-BMX-OS01 induces oxidative stress through the production of ROS. NBM-T-BMX-OS01 enhances Cisplatin-induced cell proliferation inhibition, colony formation inhibition, apoptosis (apoptosis) and cell cycle arrest. NBM-T-BMX-OS01 inhibits VEGF-induced phosphorylation of VEGFR2 and FAK. NBM-T-BMX-OS01 inhibits VEGF-induced endothelial cell proliferation, migration and tube formation, as well as microvessel sprouting in rat aortic rings and angiogenesis induced by colorectal cancer cells. NBM-T-BMX-OS01 inhibits the growth of subcutaneous colorectal cancer xenografts in nude mice. NBM-T-BMX-OS01 can be used in studies related to lung cancer, colorectal cancer and angiogenesis .

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Osthole (Standard)

Cat. No.: HY-N0054R

CAS No.: 484-12-8

Synonyms: Osthol (Standard); NSC 31868 (Standard)

Category:

Coumarins Phenylpropanoids Plants Other Families Extract

Target:

Reference Standards Histamine Receptor Apoptosis Parasite HBV

Osthole (Standard) is the analytical standard of Osthole. This product is intended for research and analytical applications. Osthole (Osthol) is a natural antihistamine alternative. Osthole may be a potential inhibitor of histamine H1 receptor activity. Osthole also suppresses the secretion of HBV in cells.

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