26 Results for "

Oxindole

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "Oxindole" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-Y0061
CAS No.: 59-48-3
Synonyms: 2-Indolinone
Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N0901
CAS No.: 6877-32-3
Corynoxine, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria rhynchophylla. Corynoxine is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
loading...
    loading...
Cat. No.: HY-59227
CAS No.: 99365-40-9
Synonyms: 6-Bromo-2-Oxindole
6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
loading...
    loading...
Cat. No.: HY-W009666
CAS No.: 118289-55-7
Target:  

Dopamine Transporter

Research Areas:  

Others

6-Chloro-5-(2-chloroethyl)oxindole (Imp Z2) is an impurity of Ziprasidone (HY-14542), a substrate of the human dopamine transporter (hDAT) .
loading...
    loading...
Cat. No.: HY-120720
CAS No.: 4963-01-3
Isomitraphylline, an oxindole alkaloid, has potent anti-cancer activity .
loading...
    loading...
Cat. No.: HY-N9163
CAS No.: 6899-73-6
Uncarine A is a oxindole alkaloid, which can be isolated from Ulzcaria berlzaysii F. Muell .
loading...
    loading...
Cat. No.: HY-116959
CAS No.: 259667-25-9
Target:  

GHSR

Research Areas:  

Metabolic Disease

SM-130686 is an oxindole derivative and an active GH secretagogue (GHS). SM-130686 stimulates GH release with a Half-maximum stimulation of 6.3 nM. SM-130686 has an orally active .
loading...
    loading...
Cat. No.: HY-N4156
CAS No.: 5629-60-7
Pteropodine (compound 3) is a monoterpenoid oxindole alkaloid that can be isolated from Hamelia patens. Pteropodine modulates the functions of M1 muscarinic and 5-HT2 receptors. Pteropodine has antioxidant and antimutagenic properties .
loading...
    loading...
Cat. No.: HY-N16467
CAS No.: 14019-66-0
Synonyms: Speciofiline
Uncarine F (Speciofiline) is a pentacyclic oxindole alkaloid found in Uncaria tomentosa. Uncaria alkaloids have wide medicinal properties, including neuroprotective, anticancer, and antihypertensive activities. Uncaria alkaloids may stimulate the immune system, relax smooth muscles, dilate blood vessels, and act as a diuretic. Uncarine F can be used for the researches of cancer, immunology, cardiovascular and neurological disease .
loading...
    loading...
Cat. No.: HY-W746828
CAS No.: 2724918-56-1
Oxindole-3-acetic acid- 13C6 is 13C labeled Oxindole-3-acetic acid .
loading...
    loading...
Cat. No.: HY-Y0061R
CAS No.: 59-48-3
Synonyms: 2-Indolinone (Standard)
Oxindole (Standard) is the analytical standard of Oxindole. This product is intended for research and analytical applications. Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.
loading...
    loading...
Cat. No.: HY-108444
CAS No.: 1137967-28-2
Purity:  99.62%
Target:  

VEGFR

Research Areas:  

Cancer

(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM .
loading...
    loading...
Cat. No.: HY-108444A
CAS No.: 884338-18-5
Target:  

VEGFR

Research Areas:  

Cancer

(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM .
loading...
    loading...
Cat. No.: HY-115943
CAS No.: 2907774-88-1
Target:  

CDK

Research Areas:  

Cancer

Anticancer agent 30 (compound 6f-Z), a 3-arylidene-2-oxindole derivative, is a selective CDK2 inhibitor with potent anticancer activity .
loading...
    loading...
Cat. No.: HY-169359
Target:  

Ligands for E3 Ligase

Research Areas:  

Others

4-Methylphenoxyacetic acid-Oxindole-CF3 is the E3 ligase ligand part of L134 (HY-169358). 4-Methylphenoxyacetic acid-Oxindole-CF3 can be utilized in PROTAC synthesis .
loading...
    loading...
Cat. No.: HY-117034
CAS No.: 106466-66-4
Rankinidine is an oxindole alkaloid that is isolated from the MeOH extract of the stem of Gelsemium rankinii .
loading...
    loading...
Cat. No.: HY-114023
CAS No.: 851681-89-5
Research Areas:  

Neurological Disease

BML-288 (compound Oxindole 1) is a potent PDE2 inhibitor with an IC50 value of 40 nM. BML-288 has the potential for the research of osteoarthritis pain .
loading...
    loading...
Cat. No.: HY-N0901B
Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway .
loading...
    loading...
Cat. No.: HY-153556
CAS No.: 388627-21-2
Purity:  98.05%
Target:  

CDK VEGFR Src

Research Areas:  

Others

GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively .
loading...
    loading...
Cat. No.: HY-Z0036R
CAS No.: 21905-78-2
Target:  

Reference Standards

N-Acetyl-2-oxindole (Standard) is the analytical standard of N-Acetyl-2-oxindole. This product is intended for research and analytical applications.
loading...
    loading...