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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
P2 ligand
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "P2 ligand" in MCE Product Catalog:
Cat. No.: HY-175031
Target:
Research Areas:
GRL-07524 (Compound 4e) is a potent inhibitor of HIV-1 protease (Ki = 0.22 nM). GRL-07524 contains oxaspirocyclic carbamates as the P2 ligands. GRL-07524 exhibits good antiviral activity with an EC50 = 210 nM. GRL-07524 binds to the HIV-1 PR active site in one of the four symmetry independent molecules along with key catalytic residues .
Cat. No.: HY-174977
Target:
Research Areas:
P2Y12R ligand-1 (Compound 41) is a high-affinity P2Y12R ligand with a Ki value of 17.1 nM. P2Y12R ligand-1 labeled with [ 18F] can be used in studies of brain PET imaging .
Cat. No.: HY-P0260
CAS No.: 142606-55-1
Target:
Cat. No.: HY-174153
CAS No.: 1404529-43-6
Target:
Research Areas:
PSB-22219 is a highly selective non-nucleotidic ligand acting on P2Y12 receptors (KD=4.57 nM). PSB-22219 is promising for research of P2Y12 receptor-associated neuroinflammation .
Cat. No.: HY-P703172
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: P2RX3; Purinergic Receptor P2X, ligand Gated Ion Channel, 3; Purinergic Receptor P2X 3; Purinergic Receptor P2X3; P2X3; P2X Receptor, Subunit 3; P2X Purinoceptor 3; Purinergic Receptor; ATP Receptor; Purinoceptor P2X3; Purinergic Receptor P2X, ligand-Gate
Species:
Human
Source:
HEK293
Cat. No.: HY-P705903
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: P2RX7; Purinergic Receptor P2X, ligand Gated Ion Channel, 7; Purinergic Receptor P2X 7; Purinergic Receptor P2X7; P2X7; Purinergic Receptor; Purnergic Receptor P2X 7; P2X Purinoceptor; P2X Purinoceptor 7; P2X7 Isoform Q; ATP Receptor; P2X7 Isoform O; P2Z Receptor; P2X7 Isoform N; MGC20089; P2X7 Receptor; Purinergic Receptor P2X, ligand-Gated Ion Channel, 7
Species:
Human
Source:
E. coli
Cat. No.: HY-189243
Target:
Research Areas:
P2Y2R antagonist-2 is an antagonist of the P2Y2 receptor (P2Y2R), with a pKi value of 6.53 for human P2Y2R. P2Y2R antagonist-2 blocks UTPγS (HY-137603)-induced calcium mobilization, binds to the orthosteric site of P2Y2R to displace fluorescent antagonist ligands, and forms unique binding interactions. P2Y2R antagonist-2 has no structural alerts, exhibiting low lipophilicity and high lipophilic efficiency. P2Y2R antagonist-2 can be used in studies related to astrocytoma and inflammation .
Cat. No.: HY-180484
CAS No.: 2974454-59-4
Research Areas:
PKMYT1-IN-12 (Compound 4) is a selective inhibitor of PKMYT1, with an IC₅₀ of 2.6 nM. PKMYT1-IN-12 can effectively inhibit the phosphorylation of CDK1, with an IC₅₀ of 44 nM. PKMYT1-IN-12 is a target protein ligand that can be used for the synthesis of PROTAC D16-M1P2 (HY-180485) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
