1

REA Antibody (YA1848)

1 Cited Publications

Cat. No.: HY-P82103

Synonyms: BAP; Bap37; BCAP 37; D prohibitin; P22; Phb2; PNAS 141; Prohibitin 2

Host:

Rabbit

Application:

WB, IHC-F, IHC-P, ICC/IF

Reactivity:

Human, Mouse, Rat

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1

NOX2 Antibody

1 Cited Publications

Cat. No.: HY-P81195

Synonyms: AMCBX2; CGD; CGD91-phox; CY24B_HUMAN; CYBB; Cytochrome b 245, beta polypeptide; Cytochrome b(558) beta chain; Cytochrome b(558) subunit beta; Cytochrome b-245 heavy chain; Cytochrome b558 subunit beta; GP91 PHOX; gp91-1; gp91-phox; GP91PHOX; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; P22 phagocyte B-cytochrome; P91 PHOX; p91-PHOX; Superoxide-generating NADPH oxidase heavy chain subunit.

Host:

Rabbit

Application:

WB, ELISA, IHC-P, IHC-F, ICC/IF

Reactivity:

Human, Mouse, Rat

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Demethylasterriquinone B1

Cat. No.: HY-107586

CAS No.: 78860-34-1

Purity: 98.10%

Synonyms: DAQ B1; L-783281; Dimethylasterriquinone

Target:

Insulin Receptor Akt NO Synthase NADPH Oxidase JAK STAT FOXO DNA/RNA Synthesis ERK Flavivirus

Research Areas:

Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology

Demethylasterriquinone B1 (DAQ B1; L-783281) is an orally active insulin receptor (insulin receptor) agonist and AKT activator. By activating AKT, Demethylasterriquinone B1 upregulates the expression and activity of eNOS to increase NO production, while downregulating the expression of the NADPH oxidase subunit p22phox to reduce oxidative stress and improve vascular endothelial dysfunction in hypertensive rats. Demethylasterriquinone B1 combind with an AKT inhibitor targets the insulin signaling pathway to activate two antiviral pathways, RNA interference and JAK/STAT, in mosquitoes, thereby reducing Zika virus infection .

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Firivumab

Cat. No.: HY-P99620

CAS No.: 1443004-15-6

Synonyms: CT-P22; CT120

Firivumab (CT-P22; CT120) is a human IgG1 monoclonal influenza A virus hemagglutinin (Anti-IAV HA) antibody. Firivumab is capable of neutralizing H1N1, H5N1, H6N1, H6N2, H8N4, H8N8, H9N2 and H12N7. Firivumab shows protection against H1N1 virus in mice .

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Peptide P2.2

Cat. No.: HY-P11040

Target:

Bacterial Antibiotic

Research Areas:

Infection

Peptide P2.2, a non-ribosomal peptide, is an antimicrobial peptide. Peptide P2.2 has potent antibacterial activity with MIC₅₀s of 4 and 32 μM for V. parahaemolyticus and V. alginolyticus, respectively. Peptide P2.2 increases synergistic antibacterial effects with antibiotics (such as Ofloxacin (HY-B0125) and Linezolid (HY-10394)) with negligible hemolytic activity. Peptide P2.2 disrupts bacterial membranes and increases permeability by modulating proteins involved in the type VI and III secretion systems. Peptide P2.2 can be used for bacterial infections research .

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NOX2-IN-2 diTFA

Cat. No.: HY-156425A

CAS No.: 2648709-80-0

Purity: 98.15%

Target:

NADPH Oxidase

Research Areas:

Inflammation/Immunology

NOX2-IN-2 diTFA (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a K_i of 0.24 μM. NOX2-IN-2 diTFA inhibits ROS production derived from NOX2 in cells .

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1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE

Cat. No.: HY-165116

CAS No.: 206059-98-5

Synonyms: 18:0p/22:6-PE; C18(Plasm)-22:6-PE; PE(P-18:0/22:6)

Target:

Endogenous Metabolite

Research Areas:

Others

1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue by mass spectrometry imaging with specific structural and distribution characteristics, and isomers of different fatty acid chains can be identified by improved methods.

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1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine

Cat. No.: HY-157695

CAS No.: 799268-64-7

Synonyms: C18(Plasm)-22:6-PC; PC(P-18:0/22:6); 18:0p/22:6-PC

Target:

Endogenous Metabolite

Research Areas:

Others

1-(1Z-Octadecenyl)-2-docosahexaenoyl-sn-glycero-3-phosphocholine (C18(Plasm)-22:6-PC) is a phospholipid identified in fish viscera by lipidomics strategy. It has different content and distribution in different fish species and can be used as an indicator of fish species differentiation.

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NOX2-IN-2

Cat. No.: HY-156425

CAS No.: 2648709-79-7

Target:

NADPH Oxidase

Research Areas:

Inflammation/Immunology

NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a K_i of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells .

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PRMT5-MTA-IN-3-d3

Cat. No.: HY-172733S

CAS No.: 3052146-54-7

Target:

Isotope-Labeled Compounds Histone Methyltransferase

Research Areas:

Cancer

PRMT5-MTA-IN-3-d₃ (compound P22) is the deuterium labeled PRMT5-MTA-IN-3 (HY-172733). PRMT5-MTA-IN-3-d₃ is an orally active PRMT5-MTA inhibitor. PRMT5-MTA-IN-3-d₃ has antiproliferative effects on HTC116-MTAP del and wild type colorectal cancer HCT-116 cell lines, with IC₅₀ values of 6 nM and 961 nM, respectively. PRMT5-MTA-IN-3-d₃ has anticancer effects, especially for MTAP-deficient tumors, such as non-small cell lung cancer (NSCLC), pancreatic cancer .

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