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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
PABP1
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "PABP1" in MCE Product Catalog:
15
15 Publications Verification
Target:
Research Areas:
EZM 2302 is a potent and orally active CARM1 inhibitor with an IC50 value of 6 nM. EZM 2302 shows antiproliferative activity and anti-tumor activity. EZM 2302 inhibits PABP1 and SMB expression [1].
4
4 Cited Publications
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Research Areas:
CARM1-IN-1 (compound 7g) is a highly potent and selective inhibitor of CARM1 (IC50=8.6 μM, CARM1/PABP1), with low inhibitory activity against PRMT1 and SET7 (IC50 >667 μM). CARM1-IN-1 inhibits the methylation activity of CARM1 and the methylation levels of different substrates, such as PABP1, CA150, SmB, and H3. CARM1-IN-1 also inhibits the promoter activity of prostate-specific antigen (PSA) without significant cytotoxicity [1].
4
4 Cited Publications
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Research Areas:
CARM1-IN-1 (compound 7g) hydrochloride is a highly potent and selective inhibitor of CARM1 (IC50=8.6 μM, CARM1/PABP1), with low inhibitory activity against PRMT1 and SET7 (IC50 >667 μM). CARM1-IN-1 hydrochloride inhibits the methylation activity of CARM1 and the methylation levels of different substrates, such as PABP1, CA150, SmB, and H3. CARM1-IN-1 hydrochloride also inhibits the promoter activity of prostate-specific antigen (PSA) without significant cytotoxicity [1].
Cat. No.: HY-P705936
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PABPC1; PABP; Prev. PABPC2; Poly(A) Binding Protein, Cytoplasmic 2; Prev. PAB1; Polyadenylate-Binding Protein; PABP1; Poly(A)-Binding Protein 1; Polyadenylate-Binding Protein 1; PABP-1; PABPL1; Poly(A) Binding Protein Cytoplasmic 1; Poly(A)-Binding Protei
Species:
Human
Source:
E. coli
Cat. No.: HY-P87003
Synonyms: PAB 1 antibody; PAB1 antibody; PABP 1 antibody; PABP-1 antibody; PABP1 antibody; PABP1_HUMAN antibody; PABPC 1 antibody; PABPc1 antibody; PABPC2 antibody; PABPL1 antibody; PAB 1 antibody; PAB1 antibody; PABP 1 antibody; PABP-1 antibody; PABP1 antibody; PABP1_HUMAN antibody; PABPC 1 antibody; PABPc1 antibody; PABPC2 antibody; PABPL1 antibody; Poly A binding protein 1 antibody; Poly A binding protein cytoplasmic 1 antibody; poly(A) binding protein, cytoplasmic 1 antibody; poly(A) binding protein, cytoplasmic 2 antibody; Poly(A)-binding protein 1 antibody; Polyadenylate binding protein 1 antibody; Polyadenylate-binding protein 1 antibody;
Cat. No.: HY-111109R
CAS No.: 1628830-21-6
Research Areas:
EZM 2302 (Standard) is the analytical standard of EZM 2302 (HY-111109). This product is intended for research and analytical applications. EZM 2302 is a potent and orally active CARM1 inhibitor with an IC50 value of 6 nM. EZM 2302 shows antiproliferative activity and anti-tumor activity. EZM 2302 inhibits PABP1 and SMB expression [1].
Cat. No.: HY-RS09948
Target:
Research Areas:
PABPC1 Human Pre-designed siRNA Set A contains three designed siRNAs for PABPC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26013
Target:
Research Areas:
Pabpc1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pabpc1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19518
Target:
Research Areas:
Pabpc1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pabpc1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
