25 Results for "

PAF-r

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "PAF-r" in MCE Product Catalog:

45
C16-PAF
C16-PAF
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45 Publications Verification
Cat. No.: HY-108635
CAS No.: 74389-68-7
Purity:  99.85%
Synonyms: PAF (C16)
Category:  

Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

p38 MAPK MEK ERK Endogenous Metabolite

C16-PAF (PAF (C16)), a phospholipid mediator, is a platelet-activating factor and ligand for PAF G-protein-coupled receptor (PAFR). C16-PAF exhibits anti-apoptotic effect and inhibits caspase-dependent death by activating the PAFR. C16-PAF is a potent MAPK and MEK/ERK activator. C16-PAF induces increased vascular permeability .
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3
Apafant
Apafant
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3 Cited Publications
Cat. No.: HY-108634
CAS No.: 105219-56-5
Purity:  99.93%
Synonyms: WEB 2086
Target:  

Platelet-activating Factor Receptor (PAFR)

Research Areas:  

Inflammation/Immunology

Apafant (WEB 2086), a chemical probe, is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM. Apafant increases the gene expression of PAF-r, α-globin, β-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit .
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3
Rilapladib
Rilapladib
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3 Cited Publications
Cat. No.: HY-102004
CAS No.: 412950-08-4
Purity:  99.44%
Synonyms: SB 659032
Target:  

Phospholipase

Research Areas:  

Neurological Disease Inflammation/Immunology

Rilapladib (SB 659032) is a selective Lp-PLA2 (lipoprotein-associated phospholipase A2) inhibitor with an IC50 of 230 pM . Rilapladib (SB 659032) is also a PAFR (Platelet Activating Factor Receptor) antagonist .
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PAF (C18)
PAF (C18)
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Cat. No.: HY-130345
CAS No.: 74389-69-8
Purity:  99.00%
Target:  

Platelet-activating Factor Receptor (PAFR)

Research Areas:  

Cardiovascular Disease

C18-PAF, octadecane PAF, is the ligand of platelet-activating factor and PAF G protein-coupled receptor (PAFR). C18-PAF has renovasodilator properties and antihypertensive lipid properties. C18-PAF increases renal blood flow and causes dose-dependent systemic hypotension .
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F-0401
F-0401
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Cat. No.: HY-177598
CAS No.: 123852-99-3
Target:  

Calcium Channel Platelet-activating Factor Receptor (PAFR)

Research Areas:  

Neurological Disease

F-0401 is a calcium antagonist with platelet-activating factor receptor (PAFR) antagonistic action. F-0401 can be used for the research of neurological disease, such as stroke .
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MK 287
MK 287
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Cat. No.: HY-106899
CAS No.: 135947-75-0
Target:  

Platelet-activating Factor Receptor (PAFR)

Research Areas:  

Cardiovascular Disease

MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis .
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Apafant-d8
Apafant-d8
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Cat. No.: HY-108634S
CAS No.: 1185101-22-7
Synonyms: WEB 2086-d8
Apafant-d8 is the deuterium labeled Apafant. Apafant (WEB 2086) is a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Kiof 9.9 nM. Apafant increases the gene expression of PAF-r, α-globin, β-globin, decreases the c-myb gene expression. Apafant shows a protective effect on alkyl-PAF-mediated lethalit .
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Ptafr Rat Pre-designed siRNA Set A
Ptafr Rat Pre-designed siRNA Set A
Cat. No.: HY-RS11349
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Ptafr Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptafr gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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PTAFR Human Pre-designed siRNA Set A
PTAFR Human Pre-designed siRNA Set A
Cat. No.: HY-RS11347
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

PTAFR Human Pre-designed siRNA Set A contains three designed siRNAs for PTAFR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Ptafr Mouse Pre-designed siRNA Set A
Ptafr Mouse Pre-designed siRNA Set A
Cat. No.: HY-RS11348
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Ptafr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptafr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Piperulin A
Piperulin A
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Cat. No.: HY-N11932
CAS No.: 164268-04-6
Category:  

Piperaceae Extract Lignans Phenylpropanoids Plants 500 - Internal Server Error | MedChemExpress

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