Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
PAQR7
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "PAQR7" in MCE Product Catalog:
Cat. No.: HY-RS10034
Target:
Research Areas:
PAQR7 Human Pre-designed siRNA Set A contains three designed siRNAs for PAQR7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Synonyms: 10-Ethenyl-19-norprogesterone
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Org OD 02-0 (10-Ethenyl-19-norprogesterone) is a selective mPRα/PAQR7 agonist that can cross the blood-brain barrier. Org OD 02-0 targets mPRα with an IC50 of 33.9 nM and activates the PI3K-AKT, MAPK/ERK, and Src signaling pathways. Org OD 02-0 upregulates SERCA2, phosphorylates phospholamban, increases sarcoplasmic reticulum calcium uptake, decreases RhoA/ROCK activity, and induces vascular smooth muscle relaxation and nitric oxide production. Org OD 02-0 can be used for research on Parkinson's disease, glioblastoma, apnea, and hypertension [7] .
Cat. No.: HY-P705640
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PAQR7; Progesterone And AdipoQ Receptor Family Member 7; Progestin And AdipoQ Receptor Family Member 7; Membrane Progesterone P4 Receptor Alpha; Progestin And AdipoQ Receptor Family Member VII; Membrane Progesterone Receptor Alpha; Membrane Progestin Rece
Species:
Human
Source:
E. coli Cell-free
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
