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DSPE-PEG2000-Mannose

1 Cited Publications

Target:

Biochemical Assay Reagents Liposome Small Interfering RNA (siRNA)

Research Areas:

DSPE-PEG2000-Mannose is a mannose-containing lipid. DSPE-PEG2000-Mannose is used to prepare mannose-conjugated Liposome (Man-lipo) for siRNA delivery. Mannose-modified liposomes encapsulating IDO siRNA (Man-lipo-siIDO) preferentially knock down IDO expression in the draining lymph nodes and spleens of melanoma-bearing mice. Man-lipo-siIDO delays the onset time of melanoma and reduces tumor volume .

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DSPE-PEG2000-ANG

Cat. No.: HY-172699

Target:

Liposome LDLR

Research Areas:

Cancer

DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties .

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Ecraprost

Cat. No.: HY-19167

CAS No.: 136892-64-3

Synonyms: AS 013; Lipo-pro-prostaglandin E1

Target:

Prostaglandin Receptor

Research Areas:

Inflammation/Immunology

Ecraprost is a prodrug of prostaglandin E1. Ecraprost inhibits platelet adhesion, macrophage infiltration and proliferating cell nuclear antigen positive cell expression on the injured arterial walls .

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Timegadine

Cat. No.: HY-100125

CAS No.: 71079-19-1

Synonyms: SR1368

Target:

COX

Research Areas:

Inflammation/Immunology

Timegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC₅₀s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets.

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Timegadine hydrochloride

Cat. No.: HY-100125A

CAS No.: 71080-06-3

Synonyms: SR1368 hydrochloride

Target:

COX

Research Areas:

Inflammation/Immunology

Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine (HY-100125). Timegadine hydrochloride is an orally active inhibitor for COX and lipo-oxygenase, that inhibits COX in washed rabbit platelets and rat brain with IC₅₀ of 5 nM and 20 μM, inhibits lipo-oxygenase in in horse and washed rabbit platelets with IC₅₀ of 100 μM. Timegadine hydrochloride exhibits anti-arthritis activity .

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Lipo-PtIV-R8K

Cat. No.: HY-P11218

Target:

Inhibitory Antibodies

Research Areas:

Cancer

Lipo-PtIV-R8K is a nuclear targeting peptide containing R8K. Lipo-PtIV-R8K is a lipid PtIV prodrug amphiphilic molecule that can self assemble to form nanoparticles. Lipo-PtIV-R8K can be used in the research of cancer such as breast cancer .

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