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78 Results for "

PDK-1

" in MedChemExpress (MCE) Product Catalog:

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BX795

42 Publications Verification

Cat. No.: HY-10514

CAS No.: 702675-74-9

Purity: 99.84%

Target:

PDK-1 IKK Autophagy

Research Areas:

Cancer

BX795 is a potent and selective inhibitor of PDK1, with an IC₅₀ of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKε, with an IC₅₀ of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKCδ, and GSK3β, and has lower selectivity over PKA, PKC, c-Kit, GSK3β etc. BX795 modulates autophagy ^[1] .

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