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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
492 Results for "
PEG chain
" in MedChemExpress (MCE) Product Catalog:
Products (492)
492 Results for "PEG chain" in MCE Product Catalog:
21
21 Publications Verification
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ALC-0159 presents highly mobile surface PEG chains in a dense brush-like conformation, which can form a hydrophilic barrier, reduce non-specific protein adsorption and macrophage uptake, improve colloidal stability, prolong in vivo circulation time, and affect the cellular uptake of LNPs. ALC-0159 dissociates from the surface of mRNA-LNPs under long-term mechanical oscillation stress, thereby reducing steric hindrance, inducing mRNA-LNP fusion, increasing particle size, and releasing unencapsulated mRNA .
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1 Cited Publications
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DBCO-PEG24-NHS ester is a click chemistry reagent. DBCO-PEG24-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
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1 Cited Publications
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DBCO-PEG2-NHS ester is a click chemistry reagent containing an azide group. DBCO-PEG2-NHS ester is a click chemistry PEG reagent containing NHS ester that is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and provides a long and flexible connection that minimizes steric hindrance involved with ligation. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research use only .
Cat. No.: HY-174968B
Synonyms: 4-Arm-PEG10000-Acrylate
Cat. No.: HY-W1049061
Cat. No.: HY-140232B
Cat. No.: HY-139322
CAS No.: 35179-86-3
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PEG-8 laurate is a single chain surfactant. PEG-8 laurate reduces the skin barrier, and acts as a penetration enhancer. PEG-8 laurate can be used to synthesize elastic vesicles .
Cat. No.: HY-W1048542
Cat. No.: HY-N16289
CAS No.: 3091879-22-7
DSPE-PEG8 Maleimide sodium is a PEG lipid containing DSPE, a polyethylene glycol chain consisting of eight ethylene glycol units (PEG8), and a maleimide group (Mal). DSPE-PEG8 Maleimide sodium can be used to prepare lipid nanoparticles for drug delivery .
Cat. No.: HY-W144703
CAS No.: 3241-20-1
Synonyms: 9-Aminoheptadecane
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Heptadecan-9-amine (9-Aminoheptadecane) is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.
Cat. No.: HY-174885B
Cat. No.: HY-W1123940A
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DMG-PEG2000-OH is a pegylated lipid. DMG-PEG2000-OH features a hydrophobic dimyristoyl glycerol anchor (C14 chains) attached to a hydrophilic polyethylene glycol chain (MW 2000). DMG-PEG2000-OH is widely used as an excipient to formulate lipid nanoparticles (LNPs) and liposomes for drug and RNA delivery.
Cat. No.: HY-W440945
Stearic acid-PEG2000-amine is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The terminal amine can react with an NHS ester to form a stable amide linkage. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer. Reagent grade, for research use only.
Cat. No.: HY-140232D
Cat. No.: HY-W190939
CAS No.: 35056-97-4
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C11-PEG9-alcohol is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W190941
CAS No.: 92691-26-4
Synonyms: 3,6,9,12,15-Pentaoxahexacosan-1-ol
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C11-PEG6-alcohol (3,6,9,12,15-Pentaoxahexacosan-1-ol) is a linker with an aliphatic carbon chain and a PEG chain. The hydrophilic PEG chain increases the water solubility of the compounds in the aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W440953
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Stearic acid-PEG1000-CH2CO2H is an amphiphilic PEG polymer which forms micelles in an aqueous solution. The aliphatic chain of stearic acid can be used to encapsulate or congregate hydrophobic therapeutic agents while the PEG chain enhances overall solubility of the polymer.
Cat. No.: HY-174885A
Cat. No.: HY-174885C
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
