3 Results for "

PGD2-d4

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "PGD2-d4" in MCE Product Catalog:

Prostaglandin D2-d4
Prostaglandin D2-d4
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Cat. No.: HY-101988S
CAS No.: 211105-29-2
Synonyms: PGD2-d4
Prostaglandin D2-d4 is the deuterium labeled Prostaglandin D2. Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals . Prostaglandin D2 is one of the most potent endogenous sleep promoting substances . PGD2 plays a protective role by suppressing inflammation .
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15-deoxy-Δ12,14-Prostaglandin D2-d4
15-deoxy-Δ12,14-Prostaglandin D2-d4
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Cat. No.: HY-116028S1
CAS No.: 2750534-91-7
Synonyms: 15-Deoxy-Δ12,14-PGD2-d4
15-Deoxy-Δ12,14-Prostaglandin D2-d4 (15-Deoxy-Δ12,14-PGD2-d4) is the deuterium labeled 15-deoxy-Δ12,14-Prostaglandin D2. 15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2) is a metabolite of prostaglandin D₂ (PGD₂) (HY-101988), which can undergo further dehydration metabolism to 15-deoxy-Δ12,14-PGJ₂. 15-deoxy-Δ12,14-Prostaglandin D2 is a highly selective agonist for DP2 receptor and PPARγ. 15-deoxy-Δ12,14-Prostaglandin D2 causes morphological changes in eosinophils and migration of type II innate lymphoid cells (ILC2). 15-deoxy-Δ12,14-Prostaglandin D2 has a growth inhibitory effect on prostate cancer cells expressing PPARγ, induces cell cycle arrest and promotes apoptosis. 15-deoxy-Δ12,14-Prostaglandin D2 can be used in related research on asthma and prostate cancer.
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13,14-Dihydro-15-keto prostaglandin D2-d4
13,14-Dihydro-15-keto prostaglandin D2-d4
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Cat. No.: HY-118830S
Synonyms: DK-PGD2-d4; 15-Oxo-13,14-dihydro-PGD2-d4; 13,14-Dihydro-15-keto-PGD2-d4
Target:  

Isotope-Labeled Compounds Drug Metabolite Prostaglandin Receptor

Research Areas:  

Inflammation/Immunology

13,14-Dihydro-15-keto prostaglandin D2-d4 (DK-PGD2-d4; 15-Oxo-13,14-dihydro-PGD2-d4; 13,14-Dihydro-15-keto-PGD2-d4) is the deuterated-labeled 13,14-Dihydro-15-keto prostaglandin D2 (HY-118830). 13,14-Dihydro-15-keto prostaglandin D2 (DK-PGD2; 15-Oxo-13,14-dihydro-PGD2; 13,14-Dihydro-15-keto-PGD2) is a metabolite of Prostaglandin D2 (HY-101988) and acts as a CRTH2 agonist. 13,14-Dihydro-15-keto-prostaglandin D2 exhibits binding activity to CRTH2, induces cellular calcium signaling flux, and mediates eosinophilia in vivo. 13,14-Dihydro-15-keto-prostaglandin D2 activates the CRTH2 receptor, triggering Gi-dependent intracellular calcium mobilization and promoting the migration and recruitment of leukocytes from bone marrow to peripheral blood in vivo. 13,14-Dihydro-15-keto prostaglandin D2 is used in research on inflammation-related diseases, such as bronchial asthma .
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