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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
170 Results for "
PGF
" in MedChemExpress (MCE) Product Catalog:
Products (170)
170 Results for "PGF" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: Prostaglandin F2α; PGF2α
11
11 Publications Verification
Synonyms: Prostaglandin F2α tromethamine salt; PGF2α THAM; Prostaglandin F2α THAM
3
Target:
Research Areas:
Ebopiprant (OBE022) is an oral and selective prostaglandin F2α (PGF2α) receptor antagonist, with Kis of 1 nM, 26 nM for human and rat FP receptors, respectively.
2
2 Cited Publications
Target:
Research Areas:
AL-8810 is a potent and selective antagonist of the PGF 2α receptor (FP receptor). AL-8810 is an activator of MAPK and ERK1/2. The Ki of the FP receptor of mouse 3T3 cells and rat A7r5 cells are 0.2±0.06 μM and 0.4±0.1 μM, respectively. AL-8810 can be used in the study of elevated intraocular pressure (OHT) and primary open-angle glaucoma (POAG) .
1
1 Cited Publications
Cat. No.: HY-P74627A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PGF; PlGF-2; Prev. PGFL; Placental Growth Factor, Vascular Endothelial Growth Factor-Related Protein; PLGF; Placental Growth Factor, Vascular Endothelial Growth Factor-Related Protein, Isoform CRA_a; Placenta Growth Factor; Placental Growth Factor-Like; S
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P74626
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PGF; PlGF-2; Prev. PGFL; Placental Growth Factor, Vascular Endothelial Growth Factor-Related Protein; PLGF; Placental Growth Factor, Vascular Endothelial Growth Factor-Related Protein, Isoform CRA_a; Placenta Growth Factor; Placental Growth Factor-Like; S
Species:
Human
Source:
HEK293
Cat. No.: HY-12956S
CAS No.: 34210-11-2
Synonyms: Prostaglandin F2a-d4; PGF2α-d4
Cat. No.: HY-129953
CAS No.: 38432-87-0
Synonyms: 9α,11β-PGF2α
Category:
Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-125774
CAS No.: 38344-08-0
Synonyms: 17-Phenyl trinor PGF2α
Target:
Research Areas:
Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor .
Synonyms: 13,14-Dihydro-15-keto-PGF2α
Target:
Target:
Research Areas:
17-Phenyl trinor PGF2α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF2α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF2α isopropyl ester is applicable to relevant research on glaucoma .
Cat. No.: HY-125150
CAS No.: 64603-03-8
Synonyms: 11-Deoxy-16-fluoro PGF2α
Cat. No.: HY-125774S
CAS No.: 58976-50-4
Synonyms: 17-Phenyl trinor PGF2α-d4
Cat. No.: HY-113209S
CAS No.: 211105-40-7
Synonyms: 8-iso-PGF2α-d4
Cat. No.: HY-118816
CAS No.: 714966-38-8
Synonyms: 11-epi PGF2α-EA; 11β-PGF2α-EA; 11β-Prostamide F2α
Target:
Research Areas:
11β-Prostaglandin F2α ethanolamide (11β-PGF2α-EA) is the theoretical hepatic metabolite of PGD2-EA, produced during COX-2 metabolism of the endogenous cannabinoid AEA which is found in brain, liver, and other mammalian tissues.1 AEA can be used directly by COX-2 and specific PG synthase to produce ethanolamide congeners of the classical PGs. PGD2-EA is formed in activated RAW 264.7 cells treated with AEA.
Synonyms: Iliren
Target:
Research Areas:
Tiaprost is a prostaglandin F2α (PGF2α) analogue.
Cat. No.: HY-129953F
Synonyms: PGF2α-biotin
Cat. No.: HY-114867
CAS No.: 1163135-92-9
Synonyms: 15(R)-17-phenyl trinor PGF2α ethyl amide
Target:
Research Areas:
(15R)-Bimatoprost (15(R)-17-phenyl trinor PGF2α ethyl amide) is a prostaglandin analog used to study glaucoma and ocular hypertension. (15R)-Bimatoprost is an isomer of Bimatoprost with an inverted (β) hydroxyl group on C-15 .
Cat. No.: HY-116161
CAS No.: 130273-87-9
Target:
Research Areas:
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
Cat. No.: HY-106037
CAS No.: 53764-90-2
Target:
Research Areas:
PGF2α-isopropyl ester is a Prostaglandin F2α (HY-12956) derivative, which is active in lowering the intraocular pressure (IOP) through increased uveoscleral outflow of aqueous humor. PGF2α-isopropyl ester causes side effects of conjunctival hyperemia and ocular irritation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
