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50 Results for "

PKC γ

" in MedChemExpress (MCE) Product Catalog:

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Go 6983

94 Publications Verification

Cat. No.: HY-13689

CAS No.: 133053-19-7

Purity: 99.32%

Synonyms: Gö 6983; Goe 6983

Target:

PKC

Research Areas:

Cancer

Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ, PKCδ and PKCζ with IC₅₀ of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.

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Bisindolylmaleimide I

46 Cited Publications

Cat. No.: HY-13867

CAS No.: 133052-90-1

Purity: 98.15%

Synonyms: GF109203X; Go 6850

Target:

PKC GSK-3

Research Areas:

Metabolic Disease Cancer

Bisindolylmaleimide I (GF109203X) is a cell-permeable and reversible PKC inhibitor (IC₅₀ of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I is also a GSK-3 inhibitor .

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Bisindolylmaleimide I hydrochloride

46 Cited Publications

Cat. No.: HY-13867A

CAS No.: 176504-36-2

Purity: 99.18%

Synonyms: GF109203X hydrochloride; Go 6850 hydrochloride

Target:

PKC GSK-3

Research Areas:

Metabolic Disease Cancer

Bisindolylmaleimide I (GF109203X) hydrochloride is a cell-permeable and reversible PKC inhibitor (IC₅₀ of 20 nM, 17 nM, 16 nM, and 20 nM for PKCα, PKCβI, PKCβII, and PKCγ. Bisindolylmaleimide I hydrochloride is also a GSK-3 inhibitor .

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Midostaurin

40 Cited Publications

Cat. No.: HY-10230

CAS No.: 120685-11-2

Purity: 99.91%

Synonyms: PKC412; CGP 41251

Target:

PKC VEGFR c-Kit NO Synthase Apoptosis

Research Areas:

Cancer

Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. Midostaurin inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC₅₀s ranging from 22-500 nM . Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression. Midostaurin shows powerful anticancer effects .

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