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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
PRDX3
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "PRDX3" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P71147
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PRDX3; Protein MER5 Homolog; Prev. AOP1; Prx-III; AOP-1; HBC189; Thioredoxin-Dependent Peroxide Reductase, Mitochondrial; Epididymis Secretory Sperm Binding Protein; Thioredoxin-Dependent Peroxiredoxin 3; Peroxiredoxin-3; Antioxidant Protein 1; PRO1748; S
Species:
Human
Source:
E. coli
Cat. No.: HY-RS11076
Target:
Research Areas:
PRDX3 Human Pre-designed siRNA Set A contains three designed siRNAs for PRDX3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17991
Target:
Research Areas:
Prdx3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prdx3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24462
Target:
Research Areas:
Prdx3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Prdx3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P10133
CAS No.: 847447-04-5
Target:
Research Areas:
Cat. No.: HY-P10132
CAS No.: 847447-01-2
Target:
Research Areas:
Cat. No.: HY-189247
PRDX3-IN-1 is an orally active antagonist targeting mitochondrial PRDX3 (Kd=0.514 μM), where PRDX3 is a marker of ferroptosis. PRDX3-IN-1 causes PRDX3 inactivation and disrupts mitochondrial redox homeostasis, inducing apoptosis, ROS accumulation, and a decrease in mitochondrial membrane potential. PRDX3-IN-1 inhibits cell migration and invasion, and downregulates NF-κB and VEGF signaling pathways. PRDX3-IN-1 can be used for research on non-small cell lung cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
