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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
PTK2B
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "PTK2B" in MCE Product Catalog:
1
1 Cited Publications
TL12-186 is a multi-kinase PROTAC degrader. TL12-186 recruits the CRBN E3 ubiquitin ligase to target and degrade a variety of distinct kinases, including FLT3, BTK, AURKA, PTK2B, and multiple cyclin-dependent kinases (CDKs). TL12-186 can be used in leukemia-related research [2] .
Target:
PROTACs Bcr-Abl CDK Salt-inducible Kinase (SIK) Cyclin G-associated Kinase (GAK) MAP4K MAPKAPK2 (MK2) Ferroptosis ULK LIM Kinase (LIMK)
Research Areas:
DB1113 is a multi-kinase PROTAC degrader. DB1113 induces the ubiquitination and degradation of ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2, and ULK1. DB1113 can be used to study diseases or disorders mediated by aberrant kinase activity .
Target:
PROTACs AAK1 Aurora Kinase CaMK CDK Ferroptosis Salt-inducible Kinase (SIK) LIM Kinase (LIMK) ULK NEKs
Research Areas:
DB0614 is a PROTAC based on Cereblon ligand, which is a selective and potent targeted protein degrader of NEK9 inhibitor. DB0614 can degrade ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2 and ULK1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity [2].
Cat. No.: HY-RS11402
Target:
Research Areas:
PTK2B Human Pre-designed siRNA Set A contains three designed siRNAs for PTK2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20473
Target:
Research Areas:
Ptk2b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptk2b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26981
Target:
Research Areas:
Ptk2b Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptk2b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705867
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PTK2B; Protein-Tyrosine Kinase 2-Beta; Prev. FAK2; Cell Adhesion Kinase Beta; RAFTK; Focal Adhesion Kinase 2; CADTK; CAK-Beta; CAKB; FADK 2; PYK2; PTK2B Protein Tyrosine Kinase 2 Beta; PTK; Protein Kinase B; Calcium-Regulated Non-Receptor Proline-Rich Tyr
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705866
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTK2B; Protein-Tyrosine Kinase 2-Beta; Prev. FAK2; Cell Adhesion Kinase Beta; RAFTK; Focal Adhesion Kinase 2; CADTK; CAK-Beta; CAKB; FADK 2; PYK2; PTK2B Protein Tyrosine Kinase 2 Beta; PTK; Protein Kinase B; Calcium-Regulated Non-Receptor Proline-Rich Tyr
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P706088
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PTK2B; Protein-Tyrosine Kinase 2-Beta; Prev. FAK2; Cell Adhesion Kinase Beta; RAFTK; Focal Adhesion Kinase 2; CADTK; CAK-Beta; CAKB; FADK 2; PYK2; PTK2B Protein Tyrosine Kinase 2 Beta; PTK; Protein Kinase B; Calcium-Regulated Non-Receptor Proline-Rich Tyr
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P85341
Synonyms: PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P85462
Synonyms: PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P86140
Synonyms: PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P80877
Synonyms: PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P80877A
Synonyms: PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P80290
Synonyms: FAK2, PYK2, RAFTK, PTK2B, Protein-tyrosine kinase 2-beta, Calcium-dependent tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase, Cell adhesion kinase beta, Focal adhesion kinase 2, Proline-rich tyrosine kinase 2, Related adhesion focal tyrosine kinase, CADTK, CAK-beta, CAKB, FADK 2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
