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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
PTPRT
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "PTPRT" in MCE Product Catalog:
Cat. No.: HY-RS11450
Target:
Research Areas:
PTPRT Human Pre-designed siRNA Set A contains three designed siRNAs for PTPRT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P705429
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTPRT; RPTP-Rho; Protein Tyrosine Phosphatase Receptor Type T; R-PTP-T; KIAA0283; Receptor Protein Tyrosine Phosphatase; RPTPrho; Protein-Tyrosine-Phosphatase; Receptor-Type Tyrosine-Protein Phosphatase Rho; Alternative Protein PTPRT; Receptor-Type Tyrosi
Species:
Human
Source:
HEK293
Cat. No.: HY-183573
Research Areas:
PTPRO-IN-1 is a selective, orally active PTPRO inhibitor with an IC50 of 0.16 μM. PTPRO-IN-1 exhibits IC50 values of 2.4 μM, 2.33 μM and 2.13 μM against PTPN22, PTP1B and PTPRT, respectively, and shows almost no inhibitory activity against STEP/SSH2. PTPRO-IN-1 inhibits the TLR4/NF-κB signaling pathway in macrophages, ameliorates colonic pathological conditions and suppresses the secretion of pro-inflammatory cytokines by T cells. PTPRO-IN-1 can be used for the research of inflammatory bowel disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
