country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

17 Results for "

PU.1

" in MedChemExpress (MCE) Product Catalog:

Products (17)

Sort by :

Categories

By Targets

Species:

Tags:

Sources:

Hosts:

Reactivities:

Applications:

Isotypes:

Conjugations:

Clonalities:

Modifications:

Products

DB1976 dihydrochloride

8 Publications Verification

Cat. No.: HY-135797A

CAS No.: 2369663-93-2

Purity: ≥98.0%

Target:

Apoptosis

Research Areas:

Cancer

DB1976 dihydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 dihydrochloride potently inhibits PU.1 binding (IC₅₀ of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, K_D of 12 nM) in vitro. DB1976 dihydrochloride has apoptosis-inducing effect ^[1] .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

DB2313

7 Cited Publications

Cat. No.: HY-124629

CAS No.: 2170606-74-1

Purity: 99.48%

Target:

Apoptosis

Research Areas:

Cancer

DB2313 is a potent inhibitor of transcription factor PU.1. DB2313 inhibits PU.1-dependent reporter gene transactivation with an IC₅₀ of 5 μM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects ^[1].

Compare

Please select quantity

August 31

Get Quote

View All Sizes

PU.1-IN-1

1 Cited Publications

Cat. No.: HY-W176171

CAS No.: 873588-27-3

Target:

MicroRNA

Research Areas:

Inflammation/Immunology

PU.1-IN-1 is a potent PU.1 inhibitor with an IC₅₀ of 2 nM. PU.1-IN-1 reduces rMANF-induced miR-223 expression. PU.1-IN-1 exhibits anti-inflammatory properties ^[1] .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

DB2115 tertahydrochloride

1 Cited Publications

Cat. No.: HY-124676A

CAS No.: 1366126-19-3

Purity: 99.13%

Target:

Apoptosis

Research Areas:

Cancer

DB2115 tetrahydrochloride is a highly selective PU.1 inhibitor that suppresses the binding of PU.1 to DNA (IC₅₀: 2.3 nM). DB2115 tetrahydrochloride can inhibit tumor cell proliferation and induce apoptosis. DB2115 tetrahydrochloride can be used in the research of tumors such as leukemia ^[1].

Compare