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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
PV-1
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "PV-1" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-125864B
CAS No.: 9001-32-5
Research Areas:
Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction [1].
1
1 Cited Publications
Cat. No.: HY-P700879
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: PLVAP; Fenestrated-Endothelial Linked Structure Protein; PV-1 Protein; Plasmalemma Vesicle Associated Protein; Fenestrated Endothelial-Linked Structure Protein; PV-1; Plasmalemma Vesicle-Associated Protein; FELS; Plasmalemma Vesicle Protein 1; PV1; DIAR10
Species:
Human
Source:
HEK293
Cat. No.: HY-P990803
Target:
Research Areas:
Cat. No.: HY-P10974
Target:
Research Areas:
Cat. No.: HY-178936
CAS No.: 3094174-82-7
Research Areas:
JAK2-IN-15 is an orally active, potent, selective JAK2 inhibitor (IC50 = 1.17 nM). JAK2-IN-15 can inhibit the AK2-STAT signaling pathway. JAK2-IN-15 significantly improves key pathological indicators such as hematocrit and splenomegaly in an Epoetin beta (HY-114134) (rhEPO)-induced mouse model. JAK2-IN-15 can be used for the study of Polycythemia Vera (PV) .
Target:
Research Areas:
H1PVAT is a potent and selective inhibitor of poliovirus serotypes (PV-1, PV-2, PV-3), and inhibits early stage of the replication. H1PVAT interacts with viral capsid directly and protects PV against heat inactivation [1] .
Cat. No.: HY-RS10745
Target:
Research Areas:
PLVAP Human Pre-designed siRNA Set A contains three designed siRNAs for PLVAP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22733
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Plvap Mouse Pre-designed siRNA Set A contains three designed siRNAs for Plvap gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS29247
Target:
Research Areas:
Plvap Rat Pre-designed siRNA Set A contains three designed siRNAs for Plvap gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
