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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Pd nanoparticles
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Pd nanoparticles" in MCE Product Catalog:
Cat. No.: HY-184617
Due to their unique physical and chemical properties, noble metal nanoparticles, represented by platinum, gold, silver, and palladium, have been extensively studied by many scientists. Palladium is a noble metal belonging to the platinum group elements. Its elemental form is a silvery-white transition metal, soft in texture and possessing good ductility and malleability. Palladium nanoparticles, due to their unique physical, chemical, and electronic properties, have shown remarkable application potential in multiple fields. The preparation methods for palladium nanoparticles mainly include chemical reduction and physical reduction methods. Chemical reduction generally involves adding a reducing agent to reduce palladium ions to elemental palladium. Common reducing agents used include sodium citrate, sodium borohydride, and hydrogen gas. Because the chemical reduction process is relatively fast, protective agents such as polyvinylpyrrolidone (PVP) are generally added to prevent palladium particles from agglomerating.
Cat. No.: HY-174485
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OVA mRNA (N1-Me-Pseudo UTP) is an mRNA encoding chicken ovalbumin. The substitution with N1-Me-Pseudo UTP (m1Ψ) improves protein expression and reduces innate immune response. OVA mRNA binds to the STING-activating polymer PD18 and is encapsulated in optimized lipid nanoparticles to construct an mRNA vaccine platform (PD18 LNP). This platform not only enhances the lymphatic delivery efficiency and protein expression of mRNA, but also potently adjuvates immune responses via activating the STING pathway .
Cat. No.: HY-169480
CAS No.: 3003022-09-8
Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3 +CD8 + central and CD3 +CD8 + effector memory T cells and decrease the percentage of CD3 + T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model .
RLX (PD 139530) is a PI3K/Akt/FoxO3a signaling inhibitor, possessing significant therapeutic potential in experimental colon cancer. RLX can effectively modulate the tumor microenvironment, enhancing the efficacy of cancer immunotherapy. RLX demonstrates the ability to improve the retention time of therapeutic agents within the tumor microenvironment by utilizing advanced nanoparticle delivery systems. RLX can be integrated with various treatment modalities, such as chemotherapy and radiotherapy, to enhance overall tumor therapy effectiveness .
Cat. No.: HY-116604A
CAS No.: 21314-60-3
Synonyms: Pd 139530 hydrochloride
RLX (PD 139530) hydrochloride is the hydrochloride of RLX (HY-116604). RLX is a PI3K/Akt/FoxO3a signaling inhibitor, possessing significant therapeutic potential in experimental colon cancer. RLX can effectively modulate the tumor microenvironment, enhancing the efficacy of cancer immunotherapy. RLX demonstrates the ability to improve the retention time of therapeutic agents within the tumor microenvironment by utilizing advanced nanoparticle delivery systems. RLX can be integrated with various treatment modalities, such as chemotherapy and radiotherapy, to enhance overall tumor therapy effectiveness .
Cat. No.: HY-184618
Due to their unique physical and chemical properties, noble metal nanoparticles, represented by platinum, gold, silver, and palladium, have been extensively studied by many scientists. Palladium is a noble metal belonging to the platinum group elements. Its elemental form is a silvery-white transition metal, soft in texture and possessing good ductility and malleability. Palladium nanoparticles, due to their unique physical, chemical, and electronic properties, have shown remarkable application potential in multiple fields. Surface modification of palladium nanoparticles with sodium citrate can significantly improve their dispersibility, stability, and biocompatibility, and facilitate further coupling with other biomolecules or fluorescent molecules.
Cat. No.: HY-184619
Due to their unique physical and chemical properties, noble metal nanoparticles, represented by platinum, gold, silver, and palladium, have been extensively studied by many scientists. Palladium is a noble metal belonging to the platinum group elements. Its elemental form is a silvery-white transition metal, soft in texture and possessing good ductility and malleability. Palladium nanoparticles, due to their unique physical, chemical, and electronic properties, have shown remarkable application potential in multiple fields. PEI surface modification of palladium nanoparticles can significantly improve their dispersibility, stability, and biocompatibility, and facilitate further coupling with other biomolecules or fluorescent molecules.
Cat. No.: HY-184616
Nanomaterials with sizes ranging from 1 to 100 nm are generally referred to as nanocrystals. The preparation of platinum nanocrystals with controllable morphology was first reported in 1996. Pt, Ag, Au, Rh, and other nanocrystals have been synthesized using various methods. Platinum has a face-centered cubic (fcc) structure, but unlike Ag, Au, and Pd, it rarely forms twins; most platinum nanocrystals are single-crystal structures. XFJ116 platinum nanoparticles were prepared via a chemical reduction method, exhibiting uniform size and good dispersibility, and can also provide platinum nanoparticles with amino and carboxyl terminator modifications.
Cat. No.: HY-181967
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PROTAC PARP1 degrader-5 is a PARP1 PROTAC degrader with a DC50 of 0.12 μM. PROTAC PARP1 degrader-5 hijacks the ubiquitin-proteasome system via catalytic ternary complex formation to drive sustained PARP1 degradation. PROTAC PARP1 degrader-5 induces DNA damage, drives marginal cytosolic double-stranded DNA accumulation in tumor cells, and up-regulates PD-L1 surface expression in tumor cells. PROTAC PARP1 degrader-5 shows tumor growth inhibition activity in murine melanoma models when encapsulated in lipid nanoparticles. PROTAC PARP1 degrader-5 can be used for the research of cancer, such as melanoma .
Cat. No.: HY-P11490
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
