8 Results for "

Phenformin

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Phenformin" in MCE Product Catalog:

11
Phenformin
Phenformin
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11 Cited Publications
Cat. No.: HY-16397
CAS No.: 114-86-3
Synonyms: Phenethylbiguanide
Target:  

Mitochondrial Metabolism AMPK Apoptosis Autophagy mTOR

Research Areas:  

Neurological Disease Metabolic Disease Cancer

Phenformin (Phenethylbiguanide) is an orally active biguanide hypoglycemic agent. Phenformin inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin inhibits cancer stem cells (CSCs) and possesses potent antitumor potential .
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11
Phenformin hydrochloride
Phenformin hydrochloride
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11 Cited Publications
Cat. No.: HY-16397A
CAS No.: 834-28-6
Synonyms: Phenethylbiguanide hydrochloride
Target:  

Apoptosis mTOR Autophagy Mitochondrial Metabolism AMPK

Research Areas:  

Neurological Disease Metabolic Disease Cancer

Phenformin (Phenethylbiguanide) hydrochloride is an orally active biguanide hypoglycemic agent. Phenformin hydrochloride inhibits mitochondrial respiratory chain complex I, leading to an increased AMP/ATP ratio, activation of AMPK, and subsequent inhibition of the mTOR pathway, thereby suppressing cell proliferation, inducing apoptosis and autophagy. Phenformin hydrochloride inhibits cancer stem cells (CSCs) and possesses potent antitumor potential .
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IM176OUT05
IM176OUT05
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Cat. No.: HY-125283
CAS No.: 1643659-96-4
Purity:  99.38%
Synonyms: 2-Me-Phen hydrochloride; 2-Me-Phenformin hydrochloride
Target:  

Mitochondrial Metabolism Oxidative Phosphorylation

Research Areas:  

Metabolic Disease

IM176OUT05 (2-Me-Phen hydrochloride), a biguanide, is a mitochondrial OXPHOS inhibitor. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2 μM. IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process .
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Galegine hydrochloride
Galegine hydrochloride
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Cat. No.: HY-N0930B
CAS No.: 2368870-39-5
Category:  

Alkaloids Other Alkaloids Metabolic Disease 500 - Internal Server Error | MedChemExpress

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