400 Results for "

Phenolic compounds

" in MedChemExpress (MCE) Product Catalog:
Products (400)

400 Results for "Phenolic compounds" in MCE Product Catalog:

147
Curcumin
Curcumin
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147 Publications Verification
Cat. No.: HY-N0005
CAS No.: 458-37-7
Synonyms: Diferuloylmethane; Natural Yellow 3; Turmeric yellow
Category:  

Anti-aging Zingiberaceae Extract Food Research Plant Sunscreen Pigments Phenols Polyphenols Cosmetic Research Curcuma longa Extract Disease Research Fields Cancer

Target:  

Histone Acetyltransferase Epigenetic Reader Domain Keap1-Nrf2 Autophagy Mitophagy Influenza Virus Ferroptosis Apoptosis

Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
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39
Chlorogenic acid
Chlorogenic acid
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39 Cited Publications
Cat. No.: HY-N0055
CAS No.: 327-97-9
Synonyms: 3-O-Caffeoylquinic acid; Heriguard; NSC-407296
Category:  

Anti-aging Endogenous metabolite Infection Human Gut Microbiota Metabolites Plant Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Caprifoliaceae Extract Disease Research Fields Inflammation/Immunology Lonicera japonica Thunb. Extract Cancer

Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite

Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .
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20
Rosmarinic acid
Rosmarinic acid
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20 Cited Publications
Cat. No.: HY-N0529
CAS No.: 20283-92-5
Synonyms: Labiatenic acid
Category:  

Plant Other Phenylpropanoids Phenylpropanoids Endogenous metabolite Disease Research Fields Cancer Labiatae Extract Rosmarinus officinalis L. Extract

Target:  

Monoamine Oxidase COMT Apoptosis Endogenous Metabolite

Rosmarinic acid is a widespread phenolic ester compound in the plants. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
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17
Bisphenol A
Bisphenol A
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17 Cited Publications
Cat. No.: HY-18260
CAS No.: 80-05-7
Category:  

Phenols Polyphenols Endogenous metabolite Disease Research Fields Endocrinology

Target:  

Environmental Pollutants Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) p38 MAPK Akt

Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .
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11
Protocatechuic acid
Protocatechuic acid
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11 Cited Publications
Cat. No.: HY-N0294
CAS No.: 99-50-3
Synonyms: 3,4-Dihydroxybenzoic acid
Category:  

Leguminosae/Fabaceae Extract Plant Ketones, Aldehydes, Acids Phenols Polyphenols Senegalia catechu (L. f.) P. J. H. Hurter & Mabb./Acacia catechu (Linn. f.) Willd. Extract

Target:  

Endogenous Metabolite

Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect.
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10
Danshensu
Danshensu
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10 Cited Publications
Cat. No.: HY-N1913
CAS No.: 76822-21-4
Synonyms: Dan shen suan A; Salvianic acid A
Category:  

Plant Simple Phenylpropanols Phenols Polyphenols Salvia miltiorrhiza Bunge Extract Phenylpropanoids Disease Research Fields Cancer Labiatae Extract

Target:  

Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis

Danshensu (Dan shen suan A), an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 μM. Danshensu has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
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10
Danshensu sodium
Danshensu sodium
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10 Cited Publications
Cat. No.: HY-N1913A
CAS No.: 81075-52-7
Synonyms: Dan shen suan A sodium; Salvianic acid A sodium
Category:  

Plant Simple Phenylpropanols Phenols Polyphenols Salvia miltiorrhiza Bunge Extract Phenylpropanoids Labiatae Extract

Target:  

Keap1-Nrf2 NF-κB Reactive Oxygen Species (ROS) SARS-CoV Apoptosis

Danshensu (Dan shen suan A) sodium, an orally active phenolic compound, can induce Nrf2/HO-1 activation and inhibition of NF-κB pathway. Danshensu sodium reduces reactive oxygen species (ROS) production, upregulates antioxidant defense mechanism and inhibits intrinsic apoptotic pathway. Danshensu sodium displays a potent antiviral activity against SARS-CoV-2 with EC50 of 0.97 μM. Danshensu sodium has anti-oxidation, anti-apoptosis, anti-lung inflammatory and has the potential for COVID-19, cardiovascular and cerebrovascular diseases research .
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9
Olive oil
Olive oil
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9 Cited Publications
Cat. No.: HY-108749
CAS No.: 8001-25-0
Synonyms: Cropure OL
Olive oil (Cropure OL) is an oleaginous compound found in the fruit of the Olea europaea tree . Olive oil contains many phenolic components and exerts antioxidant activity. Olive oil exhibits hydroxyl radical scavenging, platelet aggregation inhibition and xanthine oxidase inhibitory activity. Olive oil can promote wound healing and relieve inflammation. Olive oil can be used for the research of inflammation, cancer, metabolic and cardiovascular disease, such as diabetic foot ulcers and inflammatory bowel disease .
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6
Cryptochlorogenic acid
Cryptochlorogenic acid
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6 Cited Publications
Cat. No.: HY-N0787
CAS No.: 905-99-7
Synonyms: 4-Caffeoylquinic acid; 4-O-Caffeoylquinic acid
Category:  

Moraceae Extract Morus alba Linn. Extract Endogenous metabolite Plant Simple Phenylpropanols Other Diseases Phenols Polyphenols Phenylpropanoids Disease Research Fields

Target:  

Endogenous Metabolite NF-κB Keap1-Nrf2 mTOR HIF/HIF Prolyl-Hydroxylase

Cryptochlorogenic acid (4-Caffeoylquinic acid) is a naturally occurring phenolic acid compound with oral effectiveness, anti-inflammatory, antioxidant and anti-cardiac hypertrophy effects. Alleviating LPS (HY-D1056) and ISO (HY-B0468) by regulating proinflammatory factor expression, inhibiting NF-κB activity, promoting Nrf2 nuclear transfer, and regulating PI3Kα/Akt/ mTOR / HIF-1α signaling pathway Induced physiological stress response .
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5
Sinapinic acid
Sinapinic acid
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5 Cited Publications
Cat. No.: HY-W009732
CAS No.: 530-59-6
Synonyms: Sinapic acid
Category:  

Plant Monophenols Simple Phenylpropanols Metabolic Disease Phenols Phenylpropanoids Other Families Extract Disease Research Fields

Target:  

HDAC Angiotensin-converting Enzyme (ACE) Reactive Oxygen Species (ROS) Apoptosis

Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC, with an IC50 of 2.27 mM , and also inhibits ACE-I activity . Sinapinic acid posssess potent anti-tumor activity, induces apoptosis of tumor cells . Sinapinic acid shows antioxidant and antidiabetic activities . Sinapinic acid reduces total cholesterol, triglyceride, and HOMA-IR index, and also normalizes some serum parameters of antioxidative abilities and oxidative damage in ovariectomized rats .
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4
Ethyl Caffeate
Ethyl Caffeate
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4 Cited Publications
Cat. No.: HY-N6966
CAS No.: 102-37-4
Category:  

Plant Phenols Polyphenols Compositae/Asteraceae Extract Disease Research Fields Bidens pilosa Extract Inflammation/Immunology Cancer

Target:  

NF-κB NO Synthase COX PGE synthase

Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin .
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3
Ethyl gallate
Ethyl gallate
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3 Cited Publications
Cat. No.: HY-N0525
CAS No.: 831-61-8
Category:  

Plant Paeoniaceae Extract Paeonia lactiflora Pall. Extract Phenols Polyphenols Disease Research Fields Cancer

Target:  

Bacterial

Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide.
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3
2-Aminoindan-2-phosphonic acid hydrochloride
2-Aminoindan-2-phosphonic acid hydrochloride
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3 Cited Publications
Cat. No.: HY-W017692
CAS No.: 1416354-35-2
Target:  

Biochemical Assay Reagents

Research Areas:  

Metabolic Disease

2-Aminoindan-2-phosphonic acid hydrochloride is a competitive phenylalanine ammonia lyase (PAL) inhibitor that significantly decreases the levels of total phenolic compounds and PheGs in plant cultured cells .
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3
2-Aminoindan-2-phosphonic acid
2-Aminoindan-2-phosphonic acid
0 Images
3 Cited Publications
Cat. No.: HY-W004494
CAS No.: 141120-17-4
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

2-Aminoindan-2-phosphonic acid is an inhibitor of phenylalanine ammonia-lyase (PAL). 2-Aminoindan-2-phosphonic acid reduces the biosynthesis and accumulation of total phenolic compounds in the suspension cell culture system of Cistanche .
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3
Broussonin E
Broussonin E
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3 Cited Publications
Cat. No.: HY-N2963
CAS No.: 90902-21-9
Category:  

Thymelaeaceae Extract Daphne giraldii Nitsche Extract Plant Phenols Polyphenols

Target:  

ERK p38 MAPK JAK STAT TNF Receptor Interleukin Related COX Arginase

Broussonin E is a phenolic compound and shows anti-inflammatory activity. Broussonin E can suppress inflammation by modulating macrophages activation statevia inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway. Broussonin E can be used for the research of inflammation-related diseases such as atherosclerosis .
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3
Curcumin (Standard)
Curcumin (Standard)
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3 Cited Publications
Cat. No.: HY-N0005R
CAS No.: 458-37-7
Synonyms: Diferuloylmethane (Standard); Natural Yellow 3 (Standard); Turmeric yellow (Standard)
Category:  

Plant Zingiberaceae Extract Phenols Polyphenols Curcuma longa Extract Microorganism

Target:  

Reference Standards Histone Acetyltransferase Epigenetic Reader Domain Keap1-Nrf2 Autophagy Mitophagy Influenza Virus Ferroptosis

Curcumin (Standard) is the analytical standard of Curcumin (HY-N0005). This product is intended for research and analytical applications. Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
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2
Protosappanin B
Protosappanin B
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2 Cited Publications
Cat. No.: HY-N0800
CAS No.: 102036-29-3
Synonyms: (-)-Protosappanin B
Category:  

Leguminosae/Fabaceae Extract Plant Caesalpinia sappan L. Extract Phenols Polyphenols Disease Research Fields Cancer

Target:  

Apoptosis

Protosappanin B is a phenolic compound extracted from Caesalpinia sappan. Anti-cancer activity . Protosappanin B induces apoptosis and causes G1 cell cycle arrest in human bladder cancer cells .
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2
Tea polyphenol
Tea polyphenol
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2 Cited Publications
Cat. No.: HY-N1925
CAS No.: 84650-60-2
Category:  

Plant Phenols Camellia sinensis (L.) O. Ktze. Extract Research on Agricultural Breeding Disease Research Fields Inflammation/Immunology Cancer Theaceae Extract Agricultural Research

Target:  

Apoptosis Autophagy

Tea polyphenol is the floorboard of phenolic compounds in tea. Tea polyphenol exhibits biological activity including antioxidant and anti-cancer activities, inhibition of cell proliferation, induction of apoptosis, cell cycle arrest and modulation of carcinogen metabolism .
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2
Acetosyringone
Acetosyringone
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2 Cited Publications
Cat. No.: HY-W009884
CAS No.: 2478-38-8
Category:  

Plant Monophenols Ketones, Aldehydes, Acids Other Diseases Phenols Other Families Extract Disease Research Fields

Target:  

Endogenous Metabolite

Acetosyringone is a phenolic compound from wounded plant cells, enables virA gene which encodes a membrane-bound kinase to phosphorylate itself and activate the virG gene product, which stimulates the transcription of other vir genes and itself . Acetosyringone enhances efficient Dunaliella transformation of Agrobacterium strains .
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2
Chebulic acid
Chebulic acid
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2 Cited Publications
Cat. No.: HY-N4170
CAS No.: 23725-05-5
Category:  

Plant Combretaceae Extract Ketones, Aldehydes, Acids Metabolic Disease Phenols Polyphenols Terminalia chebula Retz. Extract Disease Research Fields

Target:  

Keap1-Nrf2 Reactive Oxygen Species (ROS)

Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection .
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