24 Results for "

Pitavastatin

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Pitavastatin" in MCE Product Catalog:

16
16 Publications Verification
Cat. No.: HY-B0144A
CAS No.: 147511-69-1
Synonyms: NK-104
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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16
16 Publications Verification
Cat. No.: HY-B0144
CAS No.: 147526-32-7
Synonyms: NK-104 hemicalcium; Pitavastatin hemicalcium
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Cat. No.: HY-125643
CAS No.: 141750-63-2
Purity:  99.30%
Pitavastatin lactone is a major metabolite of Pitavastatin (HY-B0144A) in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase .
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Cat. No.: HY-135384
CAS No.: 586966-54-3
Purity:  98.46%
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease

tert-Buthyl Pitavastatin is the  metabolite of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor .
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Cat. No.: HY-B0144BS
Pitavastatin-d4 (sodium) is deuterium labeled Pitavastatin (sodium).
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Cat. No.: HY-135383B
CAS No.: 1159588-21-2
Target:  

Drug Isomer

Research Areas:  

Metabolic Disease

(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin Calcium (HY-B0144) .
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Cat. No.: HY-Z3150
CAS No.: 154057-56-4
Target:  

Drug Intermediate

Research Areas:  

Others

Pitavastatin impurity 1 is an impurity of Pitavastatin (HY-B0144A).
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Cat. No.: HY-B0144B
CAS No.: 574705-92-3
Synonyms: NK-104 sodium
Pitavastatin (NK-104) sodium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin sodium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin sodium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin sodium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Cat. No.: HY-B0144AS1
Synonyms: NK-104-d5 sodium
Pitavastatin-d5 (sodium) is the deuterium labeled Pitavastatin sodium. Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.
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Cat. No.: HY-135383
CAS No.: 254452-92-1
Purity:  99.94%
Research Areas:  

Cardiovascular Disease

(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin Calcium (HY-B0144). Pitavastatin Calcium is a potent HMG-CoA reductase inhibitor that can be used for the study of cardiovascular disease .
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Cat. No.: HY-135383A
CAS No.: 254452-88-5
Research Areas:  

Metabolic Disease

(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin Calcium (HY-B0144). Pitavastatin is a potent HMG-CoA reductase inhibitor .
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Cat. No.: HY-B0144R
CAS No.: 147526-32-7
Synonyms: NK-104 hemicalcium (Standard); Pitavastatin hemicalcium (Standard)
Pitavastatin (Calcium) (Standard) is the analytical standard of Pitavastatin (Calcium). This product is intended for research and analytical applications. Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Cat. No.: HY-108744
CAS No.: 956116-90-8
Research Areas:  

Cardiovascular Disease

Pitavastatin magnesium is an orally active HMG-CoA Reductase inhibitor. Pitavastatin magnesium lowers total cholesterol and low-density lipoprotein cholesterol in a hyperlipidemic rat model. Pitavastatin magnesium can be used in research on cardiovascular and cerebrovascular diseases such as hyperlipidemia .
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Cat. No.: HY-B0144S
Synonyms: NK-104-d4 hemicalcium; Pitavastatin-d4 hemicalcium
Pitavastatin-d4 (hemicalcium) is deuterium labeled Pitavastatin (Calcium). Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity[1][2][3].
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Cat. No.: HY-B0144AS3
Synonyms: NK-104-d4-1 sodium
Pitavastatin-d4-1 (NK-104-d4-1) sodium is the deuterium labeled Pitavastatin sodium (HY-B0144B). Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Cat. No.: HY-Z3150R
CAS No.: 154057-56-4
Target:  

Reference Standards

3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline (Pitavastatin Impurity) (Standard) is the analytical standard of 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline (Pitavastatin Impurity). This product is intended for research and analytical applications.
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Cat. No.: HY-125643R
CAS No.: 141750-63-2
Pitavastatin lactone (Standard) is the analytical standard of Pitavastatin lactone (HY-125643). This product is intended for research and analytical applications. Pitavastatin lactone is a major metabolite of Pitavastatin (HY-B0144A) in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase .
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Cat. No.: HY-21315
CAS No.: 185105-98-0
Target:  

Drug Intermediate

Research Areas:  

Others

Pitavastatin impurity 12 is an impurity of Pitavastatin (HY-B0144A).
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Cat. No.: HY-W742150
4-Dehydroxy-3-dehydro-pitavastatin lactone-d5 is the deuterium labeled (S,E)-6-(2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-5,6-dihydro-2H-pyran-2-one (Pitavastatin Impurity) (HY-Z3610).
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Cat. No.: HY-165668S
Synonyms: 6S-((E)-2-(2-Cyclopropyl-4-(4-fluorophenyl-2,3,5,6-d4)quinolin-3-yl)vinyl)-4R-hydroxytetrahydro-2H-pyran-2-one
Pitavastatin lactone-d4 (6S-((E)-2-(2-Cyclopropyl-4-(4-fluorophenyl-2,3,5,6-d4)quinolin-3-yl)vinyl)-4R-hydroxytetrahydro-2H-pyran-2-one) is deuterium labeled Pitavastatin lactone .
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