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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
PtK2 cell
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "PtK2 cell" in MCE Product Catalog:
Cat. No.: HY-176198
CAS No.: 2341740-85-8
BI-0319 is a potent and selective PTK2 (FAK) PROTAC degrader with an IC50 of 19 nM and a DC50 of 243 nM (in A549 cells). By bridging PTK2 and VHL E3 ubiquitin ligase, BI-0319 induces polyubiquitination of PTK2, leading to its targeted degradation via the ubiquitin-proteasome system. BI-0319 can be used in research related to liver cancer and non-small cell lung cancer .
Cat. No.: HY-122844B
CAS No.: 2761021-80-9
Synonyms: BI-853520 tosylate; IN-10018 tosylate
Ifebemtinib (tosylate) (BI-853520 (tosylate); IN-10018 (tosylate)) is a highly selective PTK2 kinase inhibitor. Ifebemtinib (tosylate) demonstrates anti-tumor activity. Ifebemtinib (tosylate) inhibits FAK autophosphorylation in prostate carcinoma cells. Ifebemtinib (tosylate) can inhibit spheroid formation and orthotopic tumor growth in vivo. Ifebemtinib (tosylate) can be studied in anticancer research such as solid tumors, breast cancer, and malignant pleural mesothelioma .
Cat. No.: HY-P705867
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PtK2B; Protein-Tyrosine Kinase 2-Beta; Prev. FAK2; cell Adhesion Kinase Beta; RAFTK; Focal Adhesion Kinase 2; CADTK; CAK-Beta; CAKB; FADK 2; PYK2; PtK2B Protein Tyrosine Kinase 2 Beta; PtK; Protein Kinase B; Calcium-Regulated Non-Receptor Proline-Rich Tyr
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705866
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PtK2B; Protein-Tyrosine Kinase 2-Beta; Prev. FAK2; cell Adhesion Kinase Beta; RAFTK; Focal Adhesion Kinase 2; CADTK; CAK-Beta; CAKB; FADK 2; PYK2; PtK2B Protein Tyrosine Kinase 2 Beta; PtK; Protein Kinase B; Calcium-Regulated Non-Receptor Proline-Rich Tyr
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P706088
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PtK2B; Protein-Tyrosine Kinase 2-Beta; Prev. FAK2; cell Adhesion Kinase Beta; RAFTK; Focal Adhesion Kinase 2; CADTK; CAK-Beta; CAKB; FADK 2; PYK2; PtK2B Protein Tyrosine Kinase 2 Beta; PtK; Protein Kinase B; Calcium-Regulated Non-Receptor Proline-Rich Tyr
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P80877
Synonyms: PtK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P85341
Synonyms: PtK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P85462
Synonyms: PtK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P86140
Synonyms: PtK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P80877A
Synonyms: PtK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro
Cat. No.: HY-P80290
Synonyms: FAK2, PYK2, RAFTK, PtK2B, Protein-tyrosine kinase 2-beta, Calcium-dependent tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase, cell adhesion kinase beta, Focal adhesion kinase 2, Proline-rich tyrosine kinase 2, Related adhesion focal tyrosine kinase, CADTK, CAK-beta, CAKB, FADK 2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
