1 Result for "

QLH11811

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "QLH11811" in MCE Product Catalog:

Cat. No.: HY-189681
CAS No.: 2595202-02-9
Target:  

EGFR

Research Areas:  

Cancer

QLH-11811 is a mutant-selective EGFR tyrosine kinase inhibitor. QLH-11811 reversibly inhibits EGFR-19del/T790M/C797S and EGFR-L858R/T790M/C797S tyrosine kinase activity (IC50 = 2.6 nM and 3.1 nM, respectively), thereby overcoming C797S-mediated drug resistance. QLH-11811 exhibits weaker inhibitory activity against wild-type EGFR than against mutant EGFR variants. QLH-11811 can be used for research on advanced non-small cell lung cancer .
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