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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
QZ2135
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "QZ2135" in MCE Product Catalog:
Cat. No.: HY-170852
QZ2135 is a CRBN-recruiting PROTAC degrader targeting RET kinase, with a DC50 of 4.7 nM. QZ2135 induces RET degradation via the ubiquitin-proteasome system, while blocking RET phosphorylation and downstream signaling pathways, thereby inhibiting the proliferation and inducing apoptosis of cancer cells expressing wild-type or mutant RET. QZ2135 is applicable for cancer research .
Cat. No.: HY-W587352
CAS No.: 87462-66-6
Target:
Research Areas:
7-Iodohept-1-yne is a PROTAC Linker that can be used to synthesize PROTAC QZ2135 (HY-170852) .
Cat. No.: HY-170854
Research Areas:
RET Ligand-Linker Conjugate-1 is the conjugate composed of a RET ligand and a linker. RET Ligand-Linker Conjugate-1 can be used for synthesis of QZ2135 (HY-170852) .
Cat. No.: HY-170853
Research Areas:
RET ligand-3 is a ligand targeting RET, which can be used to synthesize the PROTAC QZ2135 (HY-170852). RET ligand-3 inhibits the RET signaling pathway, induces apoptosis in RET-expressing cells, and exhibits in vivo anti-tumor efficacy in xenograft models. RET ligand-3 is applicable for cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
